3 citations
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November 2021 in “Frontiers in medicine” In this retrospective study at Hiroshima University, methotrexate effectively controlled ocular inflammation in Japanese patients with non-infectious uveitis over 6 to 24 months, but a high incidence of adverse effects indicates careful monitoring and dose adjustments are important.
February 2024 in “World journal of stem cells” This review highlights the potential of adipose-derived mesenchymal stem cells as a cost-effective solution for tissue restoration and regeneration in ophthalmic and oculoplastic surgeries, addressing unmet needs in reconstructive procedures.
31 citations
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October 2012 in “Archives of ophthalmology” Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.
This review discusses Limbal Mesenchymal Stem Cell Secretome therapy for ocular chemical injuries, noting its potential in reducing inflammation and corneal opacity, but reports no new clinical results.
105 citations
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February 2017 in “British Journal of Dermatology” This review discusses the range of long-term complications, including mucocutaneous, ocular, and psychological sequelae, for survivors of Stevens–Johnson syndrome and toxic epidermal necrolysis, but reports no new clinical results.
33 citations
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October 2017 in “Drug Safety” SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.
1 citations
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October 2025 in “Transfusion Medicine and Hemotherapy” This review synthesizes current evidence on platelet-rich plasma for dry eye disease and reports no new results; the authors emphasize the need for standardized trials to validate these approaches.
December 2011 in “Ophthalmology” This article discusses the potential association between Demodex and blepharitis but reports no new findings, as the authors evaluated systemic associations without data on Demodex infestation.
1 citations
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May 2025 in “Natural Products and Bioprospecting” In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.
June 2022 in “Indian Journal of Ophthalmology/Indian journal of ophthalmology” This case report of an infant with AEC syndrome highlights the importance of early and aggressive management of ocular complications to preserve vision and reduce the risk of amblyopia.
13 citations
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December 2010 in “Annales de Dermatologie et de Vénéréologie” This retrospective study in Morocco confirms that Stevens-Johnson and Lyell syndromes lead to severe ocular and unsightly mucocutaneous sequelae, significantly affecting patients' social and professional integration.
June 2026 in “Ophthalmology and Therapy” This review concluded that near-infrared and red light photobiomodulation shows potential for certain ocular conditions like age-related macular degeneration and dry eye disease, but clinical evidence is still mixed and insufficient to establish it as a standard therapy.
1 citations
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January 2025 in “Veterinary Medicine International” This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.
1 citations
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October 2024 in “Veterinary Dermatology” In this case report, researchers document the first known instance of a dog developing both uveodermatological syndrome and alopecia areata concurrently, similar to occurrences in human patients, and provide a detailed overview of the clinical presentation, diagnosis, treatment, and follow-up.
11 citations
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June 2024 in “Clinical ophthalmology” This study highlights that Demodex mites, commonly found on human skin, can cause significant eye and skin issues such as blepharitis, rosacea, and dermatitis when present in abnormally high densities, underscoring the need for targeted management strategies.
17 citations
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April 2021 in “Biointerface Research in Applied Chemistry” This review discusses nanostructured lipid carriers and their potential applications in pharmaceuticals and food, offering no new clinical findings but highlighting recent advancements and patents.
December 2025 in “Current Issues in Molecular Biology” In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.
May 2025 in “Dermatology Online Journal” This report describes a rare case of eyelash overgrowth and eyelid irritation in a woman treated with erlotinib for lung adenocarcinoma, highlighting a potential side effect of the drug.
37 citations
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June 2002 in “The Laryngoscope” This study describes the otolaryngologic manifestations and multidisciplinary management strategies for 12 patients with ectodermal dysplasia, emphasizing the importance of early recognition for effective treatment.
14 citations
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March 2015 in “Facial plastic surgery clinics of North America” This review discusses various surgical techniques for rejuvenating the aging upper face, focusing on the assessment of individual structures and their relationships, but it reports no new clinical results.
56 citations
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October 2010 in “Pediatric Clinics of North America” This article discusses various types of epidermal nevi and associated syndromes but presents no new research findings.
October 2025 in “Clinical Case Reports” This case report challenges the traditional view by documenting reversible vision loss following scalp injections of platelet-rich plasma, attributed to an inflammatory or microvascular event, treatable with corticosteroids.
May 2020 in “International journal of biology, pharmacy and allied sciences” This review discusses the correlation between vitiligo and various autoimmune, systemic, and dermatological diseases, highlighting the need to increase awareness of these comorbidities.
15 citations
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January 2019 in “Journal of the Formosan Medical Association” This case study reports that adding adalimumab to a 12-year-old VKH patient's treatment allowed for ocular inflammation remission, vision improvement, and corticosteroid tapering, suggesting escalation of immunosuppression may be critical in pediatric VKH cases.
18 citations
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February 2025 in “Drug Delivery and Translational Research” This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.
86 citations
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July 2012 in “British journal of dermatology/British journal of dermatology, Supplement” This report suggests a causal connection between hyaluronic acid filler injections and the development of xanthelasma, possibly through an inflammatory reaction that increases vascular permeability and LDL leakage.
5 citations
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October 2001 in “British Journal of Ophthalmology” This abstract describes the initial success of intralesional cidofovir for SCC treatment and states that it has not shown systemic toxicity, but it does not report new clinical trial results.
15 citations
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September 2018 in “Applied Biological Chemistry” This review discusses the development of Matrigel and its role in identifying thymosin beta 4 as a regenerative protein, without reporting new experimental findings.
1 citations
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April 2024 in “Journal of Clinical Medicine” This study found that patients with severe alopecia areata demonstrated reduced corneal sensitivity and increased corneal staining, and exhibited altered topographic and biomechanical eye parameters compared to controls, suggesting a possible increased risk of keratoconus and the necessity for regular ophthalmological exams.
1 citations
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December 2023 in “Annals of Phytomedicine An International Journal” In this review, the researchers discuss how nanoemulgel overcomes the limitations of lipophilic phytomolecules by improving their bioavailability, penetration, and therapeutic efficacy, making it a promising nanocarrier for the treatment of various health conditions.