Platelet-Rich Plasma for the Treatment of Ocular Surface Disease in Animals: A Systematic Review

January 2025 in “ Veterinary Medicine International ”

Daniel Uribe, Catalina López, Jorge U. Carmona

Studysummary This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This systematic review assesses the efficacy and safety of platelet-rich plasma (PRP) for treating ocular surface diseases in animals, focusing on corneal ulcers and keratoconjunctivitis sicca. Analyzing 14 studies involving rabbits, dogs, cats, and rats, PRP was found to improve corneal healing, reduce edema, vascularization, pain, and inflammation. However, the studies had high bias risk, small sample sizes (median n=20), and inconsistent PRP protocols, limiting definitive conclusions. While PRP shows promise, it is not yet recommended as standard care. Future research should standardize PRP preparation and conduct randomized controlled trials to better assess its therapeutic potential.

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