Platelet-Rich Plasma for the Treatment of Ocular Surface Disease in Animals: A Systematic Review

January 2025 in “ Veterinary Medicine International ”

Daniel Uribe, Catalina López, Jorge U. Carmona

TLDR PRP shows promise for eye disease in animals but needs more research before being standard care.

This systematic review evaluates the use of platelet-rich plasma (PRP) for treating ocular surface diseases in animals, such as corneal ulcers and keratoconjunctivitis sicca. Analyzing 14 studies involving rabbits and dogs, the review found that PRP significantly improved corneal healing in 12 studies, reduced edema and vascularization in 9 studies, and decreased pain and inflammation in 5 studies. However, the studies were limited by high risk of bias, small sample sizes (median n = 20), and inconsistent PRP protocols. Due to these methodological issues, PRP cannot yet be recommended as standard care. Future research should focus on standardizing PRP preparation, conducting randomized controlled trials, and transparently reporting adverse effects.

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Research cited in this study

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