June 2006 in “Basrah journal of surgery” Metformin helps induce ovulation in obese women with PCOS, but weight loss is still the main treatment.
50 citations,
March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
24 citations,
July 2019 in “Journal of Obstetrics and Gynaecology” The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.
12 citations,
August 2019 in “BMC Medical Genetics” Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
10 citations,
August 2012 in “Clinical Pharmacokinectics” Type 2 diabetes does not change how metformin works in obese pregnant women, so dosage adjustments are not needed.
3 citations,
August 2020 in “Nutrition Journal” Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.
July 2024 in “Behavioural Brain Research” Long-term finasteride treatment reduces depression and brain issues in obese male rats.
November 2023 in “European heart journal” Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.
14 citations,
August 2014 in “Applied Physiology, Nutrition, and Metabolism” A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.
10 citations,
October 2017 in “BMJ Open” The Korean study confirmed that bariatric surgery is effective for weight loss in Asians.
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
June 2024 in “Research Square (Research Square)” Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
16 citations,
January 2014 in “Obesity surgery” Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
December 2023 in “Alzheimer's & Dementia” Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.
45 citations,
September 2011 in “Journal of the European Academy of Dermatology and Venereology” Obese people have more skin problems like stretch marks and infections, which get worse with higher obesity levels.
5 citations,
August 2015 in “Bioscience, Biotechnology, and Biochemistry” Obese mice with a leptin gene mutation have a longer resting phase in their hair cycle, which may help understand certain hair loss conditions.
2 citations,
January 2017 in “Iraqi journal of medical sciences” Obese women with PCOS have lower zinc levels than non-obese ones.
1 citations,
January 2023 in “BMC Women's Health” Polycystic Ovary Syndrome (PCOS) was found in 3.86% of tenth-grade girls in Guangzhou, China, with higher rates in overweight and obese girls, suggesting diagnosis should focus on hyperandrogenemia.
May 2024 in “Journal of trace elements in medicine and biology” Overweight or obese women before pregnancy have lower iron levels in their serum and hair during early pregnancy.
October 2017 in “Journal of medical science and clinical research” Obese people are more likely to have certain skin conditions like dark patches, stretch marks, skin tags, and bumpy skin.
June 2006 in “American Journal of Epidemiology” Being obese and eating too many calories may increase the risk of kidney cancer, but physical activity doesn't seem to affect this risk.
39 citations,
August 2001 in “Clinical endocrinology” Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.
4 citations,
March 2020 in “BMC Research Notes” Skin tags in obese individuals may indicate higher cardiovascular risk.
1 citations,
May 2022 in “Journal of The American Academy of Dermatology” Some overweight or obese men with long-term frontal fibrosing alopecia may have abnormal sex hormone levels.
February 2020 in “Research Square (Research Square)” Skin tags in obese individuals may indicate a higher risk of heart disease and diabetes.
August 2019 in “Placenta” Being overweight or obese before pregnancy increases the risk of having a C-section and a larger-than-normal baby in Chile's public health system.
September 2016 in “Ege tıp dergisi/Ege tıp dergisi :” An 11-year-old obese girl was diagnosed with lipedematous scalp, a condition with swollen scalp tissue usually found in adult women.
37 citations,
October 2004 in “Adolescent Medicine Clinics” Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
31 citations,
January 2014 in “Clinical Endocrinology” The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
September 2023 in “The Journal of Dermatology” Bariatric surgery improved many skin conditions in obese patients but caused hair loss in some and decreased facial oil and skin elasticity.