May 2023 in “Sučasna pedìatrìâ. Ukraïna” In a clinical observation study, researchers documented a case of total alopecia in an 11-year-old child, highlighting a potential link to genetic conditions such as autoimmune polyendocrinopathy candidiasis-ectodermal dystrophy (APECED syndrome) requiring further genetic and serological testing to verify the diagnosis.
This study reviewed chitosan composites, specifically those with silver or zinc oxide nanoparticles, highlighting their enhanced antimicrobial efficacy and potential biomedical applications despite pure chitosan's limitations such as pH sensitivity and poor solubility.
December 2025 in “Pharmaceutics” This review highlights new perspectives in genomics and epigenomics for skin rejuvenation, comparing innovative strategies like senolytics and DNA repair modulators with classical treatments, and emphasizing the importance of tailoring therapies using individual genomic profiles for personalized anti-ageing approaches.
June 2025 in “AgroLife Scientific Journal” In a Romanian wildlife rehabilitation center, this study reported that dermatophytosis affected northern white-breasted hedgehogs, with 77.4% of the 31 treated cases responding favorably to a 14-day itraconazole regimen, emphasizing the importance of early diagnosis and treatment.
May 2025 in “Clinical and Translational Allergy” This qualitative review reports a high socioeconomic impact of atopic dermatitis and alopecia areata, emphasizing significant quality of life reductions and increased costs, but highlights a lack of comprehensive data from many regions worldwide, underscoring the need for global studies with standardized methodologies.
March 2024 in “Buletin de psihiatrie integrativă (Print)” This review identifies a significant link between telogen effluvium and increased psychological distress, including anxiety, depression, and social phobia, stressing the need for both medical and psychological care to improve affected individuals' quality of life.
December 2021 in “Acta Marisiensis” This review discusses the clinical significance, mechanisms, and treatment options of insulin resistance, emphasizing its impact on endocrine diseases and the need for further research into inflammatory cytokines.
February 2022 in “Journal of Cosmetic Dermatology” This study suggests that systemic oxidative stress in female pattern hair loss may be related to NRF2 deficiency, and NRF2 activators might assist in treatment.
16 citations
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November 2018 in “Medicinal Chemistry” The authors concluded that newly synthesized N-acyl-L-tryptophanyl-isoleucine amides showed high anxiolytic activity in animal models, comparable to diazepam, through interaction with the TSPO receptor.
12 citations
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January 2004 in “International Journal of aromatherapy/International journal of aromatherapy” This study found that Ocimum gratissimum essential oil may enhance hair growth and promote follicular proliferation in rats experiencing cyclophosphamide-induced hair loss.
10 citations
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January 1996 in “OpenDocs (Institute of Development Studies)” This conference paper reviews the use of African medicinal herbs for wound healing, emphasizing wound healing agents and their active components, but it reports no new clinical results.
6 citations
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July 2016 in “Doklady Biochemistry and Biophysics” This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.
1 citations
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April 2022 in “Journal of cosmetic dermatology” This study found that Krox20 is overexpressed in scar fibroblasts and may play a role in scar formation by upregulating genes involved in tissue remodeling and wound healing.
February 2026 in “Orphanet Journal of Rare Diseases” This study identified pathogenic or likely pathogenic gene variants in 70.1% of Russian families affected by hypohidrotic ectodermal dysplasia, expanding knowledge of causative mutations.
January 2024 in “Endocrine and metabolic science” This review explores the applicability of the current PCOS diagnostic criteria, highlighting the need to reassess these criteria in light of new evidence on the disorder's heterogeneity and potential subtypes.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that back skin mesenchyme from mouse embryos can induce hair follicle formation even before dermal condensate formation, but R-spondin-1 alone or with a Bmp receptor inhibitor was not sufficient for hair follicle induction.
December 2020 in “Èffektivnaâ farmakoterapiâ” In this study, researchers observed that a new peptide complex helped increase hair density in postmenopausal patients with female-type hair loss by promoting the transition of hair follicles from a resting stage to a growth stage.
October 2018 in “Vestnik dermatologii i venerologii” This study found that VEGF growth factor plays a significant role in the development of androgenetic alopecia and telogen hair loss in women, more so than KGF, TGF-01, or EGF.
January 2010 in “Nonlinearity in Biology Toxicology Medicine” This review assessed prior rodent studies on low-dose endocrine toxicity and found no confirmatory evidence, suggesting variability in control groups as a major confounding factor.
This study found no significant difference in serum ferritin levels between individuals with androgenetic alopecia and healthy controls, but reported lower ferritin levels in those with premature alopecia compared to adult-onset cases.
68 citations
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January 2022 in “International Journal of Molecular Sciences” This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.
28 citations
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September 2019 in “International Journal of Nanomedicine” This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.
11 citations
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May 2022 in “World Journal of Biological Chemistry” This review discusses potential benefits of adding bioidentical progesterone to gender-affirming treatment for trans women and reports no new clinical results; it calls for further research to confirm efficacy and safety.
9 citations
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March 2022 in “Antioxidants” This review summarized and classified 32 approved synthetic and natural-identical antioxidants, examining their regulatory status, safety, pharmacological properties, and effectiveness on human health, aiming to clarify their antioxidant actions and encourage further research in the field.
9 citations
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January 2017 in “Farmacia” This review discusses the safety of finasteride for male androgenic alopecia and benign prostatic hyperplasia, concluding it remains a viable option due to synergistic effects with other treatments and predictive measures for side effect risk.
5 citations
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April 2022 in “Pharmaceutics” This study reported that 5% minoxidil nanoparticles enhanced hair growth more effectively in mice than a commercial minoxidil solution, with significantly higher drug accumulation in the upper hair follicles.
2 citations
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November 2025 in “Pharmaceutics” This study found that a CLSM-based approach could semi-quantitatively assess the transdermal penetration behavior of fluorescent dyes with different lipophilicities, offering a tool for early-stage screening of compound penetration.
2 citations
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January 2023 in “Research Square (Research Square)” This study found that obesity, insulin resistance, and hyperandrogenism increase the risk of depression and food cravings in women with PCOS, exacerbating obesity and metabolic syndrome.
In this study, centralised measurements provided more consistent and accurate results for assessing hair loss in mild-to-moderate alopecia areata, reducing error compared to local ratings.
In a phase 2 trial, researchers tested a topical formulation for alopecia areata and found significant hair regrowth with the treatment, but these improvements did not lead to substantial enhancements in health-related quality of life.