In this phase 2 trial, STS01 1% significantly improved hair regrowth in patients with mild to moderate patchy alopecia areata compared to placebo, with a manageable skin irritation side effect profile.
December 2024 in “Biological and Pharmaceutical Bulletin” In this study, researchers found that minoxidil nanocrystals delivered using MG-MXD@NP, containing methylcellulose and gum arabic, significantly improved hair growth in mice compared to a standard minoxidil lotion, with enhanced delivery to skin tissues and increased markers of hair follicle stem cell activity.
February 2024 in “Internet Journal of Rheumatology and Clinical Immunology” This study examines a diagnostic case of SLE with atypical symptoms linked to thymoma-related multiorgan autoimmunity.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, N-MXD (minoxidil nanoparticles) was shown to deliver more drug into hair bulbs and enhance IGF-1 and VEGF levels more effectively than commercial formulations, resulting in higher therapeutic efficiency for hair growth in C57BL/6 mice.
July 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that finasteride delivered through a nano-transferosomal gel showed improved penetration through skin layers compared to a conventional gel, suggesting a potential alternative for oral administration.
This study found that personality characteristics are significantly related to the severity, duration, and pattern of androgenetic alopecia in women.
August 2022 in “Yakugaku zasshi” In this study, pre-treatment with steam towel, l-menthol, and CA-carpronium enhanced the absorption of minoxidil nanoparticles in mice, potentially increasing therapeutic efficiency without side effects.
415 citations
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January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
69 citations
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January 2021 in “Journal of Biological Chemistry” This review discusses various amino acid-derived plant defensive compounds and highlights their potential as drug leads due to their potent antimicrobial properties, but reports no new experimental results.
22 citations
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June 2017 in “Stem cell reports” This study found that PTEN regulates the number and genomic stability of hair follicle stem cells in the skin, with its deficiency leading to increased stem cell accumulation and senescence through interactions with BMAL1 and BMI-1.
11 citations
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April 2025 in “Pharmaceutics” In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.
10 citations
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March 2023 in “Journal of Chemistry” This study identified ten novel compounds that may effectively target steroid 5 alpha-reductase 2 (5αR-2) for potential treatment of benign prostate hyperplasia, exhibiting comparable binding energies to existing drugs like finasteride and dutasteride.
4 citations
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February 2024 in “Scientific Reports” This study found that Platelet Rich Plasma is effective as a direct pulp capping agent, comparable to Mineral Trioxide Aggregate, but with potentially better cellular dentinogenic responses and homogenous tissue formation in dogs.
In this study, a validated chromatographic method demonstrated the ability to simultaneously analyze gemcitabine and olaparib in pancreatic cancer tissues, supporting the advancement of pharmaceutical formulations combining these drugs, particularly for patients with BRCA mutations.
July 1989 in “British Journal of Dermatology” Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.
12 citations
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December 2023 in “Antioxidants” In this study, researchers found that blackberry leaves exhibited higher liposoluble antioxidant levels and inhibited lipid peroxidation more effectively than raspberry leaves, while raspberry leaves showed greater water-soluble antioxidant content and hydroxyl radical inhibition in vitro.
4 citations
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March 2022 in “Ghana Medical Journal” This study found that hair greying is prevalent among adult traders in Lagos, Nigeria, typically onset at age 30, with premature greying considered uncommon.
2 citations
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June 2025 in “Cosmetics” This study observed that a five-week topical treatment with cold-pressed Rosa canina seed oil significantly reduced mean wrinkle scores and UV-induced spots in volunteers, suggesting potential anti-aging and photoprotective benefits attributed to its high carotenoid content.
December 2025 in “Veterinary Sciences” This study suggests that ozone bagging therapy may effectively enhance the healing of chronic distal limb wounds in horses, achieving full wound closure with minimal complications.
August 2024 in “Research Journal of Health Sciences” This study reports that normal scalp and hair in Black Africans exhibited regular white dots and a preserved honeycomb pattern, with some showing peripilar casts and scales.
This study found that hair loss is common among urban market traders in Nigeria, with a higher prevalence in women and linked to hair care practices like braiding and chemical relaxing.
9 citations
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April 2024 in “Advanced Drug Delivery Reviews”
8 citations
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January 2017 in “Fertility and Sterility” This article reviews the impact of aging and related urologic conditions on male fertility, highlighting the effects of various treatments on sperm parameters and recommending pre-treatment counseling for fertility preservation. It reports no new clinical results.
2 citations
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September 2022 in “Annals of Oncology” This study observed that MIRV improved gastrointestinal symptoms and other quality of life measures in patients with platinum-resistant ovarian cancer compared to chemotherapy.
2 citations
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March 2017 in “The Australian and New Zealand journal of obstetrics and gynaecology” This study found that paternal exposures accounted for a small fraction of calls to the MotherSafe service, and highlighted the lack of reliable information on paternal exposures in publicly available resources.
January 2018 in “Springer eBooks” Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
December 2024 in “Dermatologic Surgery” This study observed that pooled analysis of LED caps increased hair density in patients with androgenetic alopecia compared to sham, achieving 28.5 more hairs per cm².
The researchers in this study observed that while hair chemical use was common among females with SLE, it was not linked to the development of SLE. However, those who used chemical hair straighteners before their SLE diagnosis had a higher risk of developing cutaneous manifestations.
April 2023 in “Journal of Investigative Dermatology” This study found that occlusive dressings on mouse wounds eliminated wound-induced hair neogenesis by upregulating mechanotransduction, which promotes fibrosis, and suppressing Wnt signaling involved in regeneration.