Advancing Immunotherapy Using Biomaterials to Control Tissue, Cellular, and Molecular Level Immune Signaling in Skin
April 2024
in “
Advanced Drug Delivery Reviews
”
Research cited in this study
8 / 8 resultsresearch Exploiting Unique Features of Microneedles to Modulate Immunity
This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.
research Tolerability, Acceptability, and Reproducibility of Topical STAR Particles in Human Subjects
This study found that STAR particles, when applied to human skin, were well tolerated and highly acceptable at various pressures and with repeated daily use, suggesting they may provide a safe and effective method for enhancing drug delivery through the skin.
research Laser-Assisted Drug Delivery: A Systematic Review of Safety and Adverse Events
This review found that laser-assisted drug delivery in humans was associated with several adverse effects, but no life-threatening events were reported in the studies examined.
research Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment
This study found that a ceria nanozyme-integrated microneedles patch accelerated hair regeneration in an androgenetic alopecia mouse model more effectively than minoxidil, with reduced application frequency and minimal skin damage.
research The Dynamics of the Skin’s Immune System
This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
research Human αβ and γδ T Cells in Skin Immunity and Disease
This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
research Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin
In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.
research Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice
In this study, the researchers found that alopecia in VDR null mice is likely due to issues with hair cycle initiation rather than defects in keratinocyte proliferation or differentiation.
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research Composite biomaterials in immunomodulation: A new era in targeted therapy
In this review, researchers explored the design of composite biomaterials for immunomodulation and their potential to influence immune cell behavior, which could be leveraged for treating diseases like cancer and improving tissue regeneration, while also addressing translational challenges such as biocompatibility and safety.
research Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing
This review discusses the immune system's role in skin repair and regeneration, highlighting how biomaterials could potentially enhance fully functional skin regeneration through immunomodulatory mechanisms, but reports no new results.
research Advances and applications of biomimetic biomaterials for endogenous skin regeneration
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research Nanomedicine-based immunotherapy for tissue regeneration
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research Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores advancements in bioprinting technologies for developing in vitro skin models that replicate immune-mediated skin diseases, highlighting their potential to reduce animal testing and enhance research and product testing capabilities in dermatology.