Progesterone in Gender-Affirming Therapy of Trans Women
May 2022
in “
World Journal of Biological Chemistry
”
Studysummary This review discusses potential benefits of adding bioidentical progesterone to gender-affirming treatment for trans women and reports no new clinical results; it calls for further research to confirm efficacy and safety.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The article explored the potential clinical implications of adding bioidentical progesterone to the gender-affirming treatment of trans women. Progesterone was expected to provide moderate anti-androgen effects, aid in breast maturation, and offer long-term benefits such as preventing bone loss and protecting cardiovascular health. These potential benefits were inferred from the hormone's biological actions in cisgender women, and the article emphasized the need for caution and further research to confirm the efficacy and safety of progesterone in hormonal regimens for trans women.
