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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

The new palladium catalyst is effective and reusable for making pharmaceutical ingredients.

Platinum compounds used in cancer treatment can cause serious side effects like organ damage and hair loss.

Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Created large amounts of grape seed compounds using a new method.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Certain drugs that block specific enzymes can help treat prostate diseases.

Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Thioglycolate lotions are the most popular method for permanent waving and hair straightening.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.

Understanding the properties of hyaluronic acid helps improve its use in facial aging treatments.

Juglone from walnut extracts may help repair damaged hair.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Understanding hair surface properties is key for effective hair care products.

The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.