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New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Mutations in certain receptors can cause diseases and offer new treatment options.

Melatonin helps hair grow by activating the RORα receptor in goats.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

The vitamin D receptor can work without its usual activating molecule.

The HR protein's role as a repressor is essential for controlling hair growth.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.