Search

everythinglearnresearchcommunity

for

Search:↓

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

A mother and daughter have a rare genetic hair loss disorder with no effective treatment.

Fat under the skin releases HGF which helps hair grow and gain color.

Allopregnanolone changes gene expression in glioblastoma cells.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Myc activation reduces skin stem cells by affecting cell adhesion.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Activating Notch signaling can kill basal cell carcinoma cells.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Vitamin D is crucial for bone health and preventing serious diseases.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.