March 2021 in “Der Hautarzt” This review covers the clinical features, pathophysiology, differential diagnoses, and therapeutic options for neuroendocrine paraneoplastic syndromes affecting the skin but reports no new clinical findings.
2 citations
,
February 2022 in “Pakistan Armed Forces Medical Journal” This study found that women with PCOS reported significant appearance-related distress and social anxiety, especially in social settings.
November 2025 in “Journal of Investigative Dermatology” PCFCL may have unrecognized subtypes and needs more research.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.
December 2025 in “Saudi Journal of Medicine and Public Health” This narrative review highlights the critical role of pharmacists in optimizing topical corticosteroid therapy through proper agent selection, dosing, and patient education to manage various steroid-responsive skin conditions effectively.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers described ONCO-NK-TRANSITION-GM1, a cancer therapy that's manufacturable with current pharmaceutical methods, showing a 60-80% complete response rate across various cancer types and costing $50 per dose, providing a more accessible alternative to existing treatments.
February 2025 in “Intisari Sains Medis” This article explores the potential mechanisms by which polydeoxyribonucleotide (PDRN) could improve skin quality, slow aging, and enhance skin regeneration, but reports no new clinical findings.
109 citations
,
April 1997 in “Archives of Dermatological Research” The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.
August 2024 in “Medicine” This study found that medroxyprogesterone acetate and ethinyl estradiol with drospirenone were the most frequently prescribed medications for PCOS, with some patients experiencing drug changes or discontinuation due to side effects or therapeutic failure.
4 citations
,
August 2025 in “Journal of Ovarian Research” This study focused on categorizing the research status of natural products for improving ovary and uterus quality, fertility, and weight loss in PCOS, but noted a lack of continuous studies connecting basic research to clinical trials.
April 2016 in “Journal of The American Academy of Dermatology” This study reported that inpatient dermatology consultations at a large tertiary care center led to treatment changes in 81.9% of cases, particularly improving management of complex cutaneous conditions associated with systemic diseases.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
10 citations
,
March 2016 in “The Journal of Obstetrics and Gynecology of India” This review proposes renaming polycystic ovarian syndrome to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" to better reflect its diagnostic criteria and promote consistency in research, but reports no new clinical findings.
3 citations
,
March 2024 in “Journal of the American Academy of Dermatology” Low-dose naltrexone helps improve symptoms and stabilize frontal fibrosing alopecia and lichen planopilaris.
August 2020 in “Research Square (Research Square)” This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.
December 2025 in “BENTHAM SCIENCE PUBLISHERS eBooks” This chapter reviews the clinical presentation of Polycystic Ovary Syndrome and its differentiation from other conditions, but reports no new clinical results.
January 2022 in “Elsevier eBooks” This study found that sodium valproate nanospanlastics could be an effective and safer method for treating androgenic alopecia, with results comparable to minoxidil but fewer side effects.
January 2026 in “Drug Delivery and Translational Research” This study investigated the integration of crystal engineering and microneedle technology for androgenetic alopecia treatment, finding that microneedles loaded with newly developed Kopexil multicomponent crystals reduced drug diffusion rates in vitro compared to standard formulations.
11 citations
,
January 2014 in “PubMed” This study found that patients with high androgen levels due to PCOS required more sessions of Nd-YAG laser therapy for hair reduction compared to those with normal or low hormone levels.
January 2025 in “Human Reproduction Open”
271 citations
,
June 2013 in “Human Reproduction” In this study, the prevalence of polycystic ovary syndrome among Han Chinese women aged 19-45 was found to be 5.6%, and PCOS was associated with increased metabolic risks, particularly in obese individuals.
In this study of Andean Ecuadorian women with PCOS, phenotypes A and B were more prevalent and associated with higher risks of insulin resistance, anovulation, and metabolic disorders compared to phenotypes C and D.
5 citations
,
January 2022 in “Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences” This review discusses the role of nanoparticles in cancer diagnosis and treatment and outlines their potential to improve outcomes by reducing systemic toxicity and overcoming multidrug resistance, though it reports no new clinical results.
November 2021 in “Research Square (Research Square)” This study optimized caffeine-loaded nanostructured lipid carriers for alopecia treatment, achieving enhanced skin permeation and promoting hair growth compared to a marketed formula, as shown through physiochemical evaluations and histological examination.
December 2025 in “Journal of Nanobiotechnology” This study introduced a novel microneedle-based system for androgenetic alopecia treatment, which delivered Ginsenoside Compound K and S-nitrosoglutathione to enhance hair regeneration by improving the hair follicle microenvironment and promoting follicular cell proliferation.
12 citations
,
February 2022 in “Frontiers in Pharmacology” This study reports that Asparagus racemosus and Withania somnifera extracts significantly reduced paclitaxel-induced myelosuppression and morbidity in mice, suggesting their potential as therapeutic adjuvants in cancer management.
57 citations
,
April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that despite the presence of steroidogenesis inhibitors, CRPC tumor cells adapt to continue synthesizing androgens, suggesting a need for more effective androgen axis targeting.
33 citations
,
October 2010 in “Journal of Dermatological Science” This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.
2 citations
,
October 2008 in “The Journal for Nurse Practitioners” This review discusses the challenges in diagnosing polycystic ovarian syndrome due to its variable clinical features and emphasizes the need for early identification and intervention to prevent metabolic complications, but reports no new clinical results.
This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.