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This study reports the first identification of the deleterious NIPAL 4 variant, associated with autosomal recessive congenital ichthyosis, in an American Bully and describes its clinical management and follow-up.

This study found that the development and differentiation of Merkel cells in C57BL mouse embryos' dorsolateral skin are linked to tylotrich follicle formation rather than to neural influences.

In this study, researchers found that the gene Dkk4 influences color pattern formation in domestic cat fetuses, and its mutation is linked to the Ticked pattern type.

This study found that Hopx labels a long-lived progenitor population in hair follicles, which contributes to hair follicle stem cell homeostasis and has an alternative origin from previously thought progenitors.

This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.

This study suggests that nestin is an important marker for identifying HMB-45-negative cells in nodular melanomas, particularly in the dermal parts.

Basonuclin helps identify and track hair follicle development and cycling in mice.

This study found that stimulating olfactory receptor OR2AT4 in human hair follicles with Sandalore® may slow catagen development and reduce keratinocyte apoptosis, suggesting potential implications for hair growth management.

This study observed nestin-GFP expressing stem cells in the hair follicle bulge of living mice using high-resolution in-vivo multiphoton tomography, allowing migration tracking within their natural skin environment.

This study identified a novel recessive mutation in mice causing lethal congenital lamellar ichthyosis, with skin and hair follicle alterations similar to human congenital ichthyoses, linked to a specific genetic defect affecting Fatp4.

In this study, the researchers found that cholinergic signaling via M4 muscarinic receptors influences hair growth, with enhanced elongation observed upon activation with bethanechol, highlighting its potential role in hair biology using mouse models.

This study found that periodic red light exposure increased histone acetylation and activated metabolic processes in aged mice, leading to enhanced fatty acid oxidation and the mitigation of cellular aging by influencing gene expression and metabolic regulation.

In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.

This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.

This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.

This study found that keratin K1014chim expression in mice did not reduce epidermal cell proliferation but increased susceptibility to benign tumors, challenging previous beliefs about K10's role in inhibiting tumor development.

The FTO gene hinders stem cells in hair follicles from becoming pigment cells.

This study identified novel compound heterozygous mutations in the DSG4 gene in a Japanese patient with congenital hypotrichosis, suggesting overlap between localized autosomal recessive hypotrichosis and monilethrix.

In this study, over-expression of FoxN1 in early life was associated with detrimental effects on thymic and skin epithelial development in mice.

In this study, periodic exposure to red light in aged mice led to increased histone acetylation and activated mitochondrial fatty acid oxidation, which collectively mitigated cellular aging by modulating metabolism, inflammation, and gene expression.

This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.

This study found that deleting Ube2n in adult mouse skin leads to inflammation and other skin changes, and identifies IRAK1/4 as potential treatment targets for inflammatory skin disorders.

This study identified transcription elongation as a crucial regulatory factor in adipocyte cell fate, showing that the elongation factors Spt4 and Spt6 are essential for proper adipogenic differentiation by aiding RNA polymerase II progression through key adipogenic genes.

This study found that the absence of Hif-p4h-2 in specific mouse skin cells disrupted hair follicle development, leading to hair loss due to irregular keratin formation and pathway signaling.

In this study, researchers observed that mice with the naked gene showed frequent absence of hair cuticle and cortical cells during follicle growth, with abnormal keratin deposition also noted.

This study found that in adult mouse skin, somatosensory axon plasticity is highly dynamic and influenced by epithelial-neural crosstalk and intrinsic neural mechanisms.

This dataset supports a study suggesting that hair follicle neural crest stem cell-derived exosomes carrying miR-214-3p may promote neurite outgrowth and aid peripheral nerve regeneration in vitro and in vivo.

This study found that ATP synthases and the mitochondrial gene COX2 play a key role in determining the size of skin appendages in hedgehogs and mice by influencing energy metabolism and cell proliferation.

This study found that NDRG1 expression increases during the proliferation of infantile hemangioma and may positively regulate its growth, while FOXO1 downregulation plays a role in its pathogenesis.

This study demonstrates that SDF-1/CXCL12 and CXCR4 signaling play a crucial role in directing the migration and positioning of melanoblasts in mouse hair follicle formation.