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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Human skin can make serotonin and melatonin.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Applying a special compound can promote hair growth without harmful side effects.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Both mouse and rat models are effective for testing alopecia areata treatments.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Mice with human skin protein K8 had more skin problems and cancer.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Finasteride reduces prostate bleeding by affecting blood vessel growth.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Mice without collagen VI have slower hair growth normally but faster regrowth after injury.