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The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Testosterone's muscle-building effects do not require its conversion to DHT.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Spironolactone most effective for hirsutism, but has side effects.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.

Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Tamoxifen effectively treats gynecomastia without causing impotence.

Endocrine therapies for cancer significantly increase the risk of hair loss.

The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.

PRP injections effectively treat hair loss, with positive results in both monthly and every three months treatments.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Certain hormone treatments can improve acne and related conditions in women.