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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Special fiber materials boost the healing properties of certain stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

People who are more materialistic often expect life changes from buying things, leading to more debt and credit misuse.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.