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The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.

Some skin conditions are common during pregnancy and can be safely treated without affecting the pregnancy outcome.

Finasteride can cause sexual problems and depression in young men.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.

Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

Healthcare providers need better education and policies to serve transgender individuals effectively.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Finasteride doesn't affect erections much, but may decrease libido in men.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.

Latanoprostene bunod effectively lowers eye pressure and is better tolerated than other glaucoma medications.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.