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150-180 / 1000+ resultsresearch Co-delivering Retinol and Niacinamide via Liposomes: Enhanced Stability, Efficient Skin Permeation, and Improved Anti-Aging/Skin-Brightening Efficacy
This study found that the RN-Lip co-delivery system enhanced the stability and skin permeation of retinol and niacinamide, leading to improved anti-aging and skin-brightening effects in vitro.
research Real-world study of adverse events associated with gepant use in migraine treatment based on the VigiAccess and U.S. Food and Drug Administration’s adverse event reporting system databases
Gepant medications for migraines show varied safety profiles in this study, with specific adverse events reported across systems like gastrointestinal and skin disorders, highlighting the need for tailored treatment and monitoring.
research Niosomal and ethosomal gels: A comparative in vitro and ex vivo evaluation for repurposing of spironolactone
This study found that Spironolactone-loaded ethosomal gels provided superior skin permeation and deposition compared to niosomal gels in rabbit skin, suggesting that ethosomal gels could be a promising formulation for further clinical studies on treating androgenic alopecia.
research ZALCITABINE
This abstract lists numerous dermatological side effects and reactions associated with various medications but reports no new research findings.
research A Clinical Trial to Investigate the Effect of Cynatine HNS on Hair and Nail Parameters
This study found that Cynatine HNS significantly improved hair and nail health in women after 90 days compared to placebo.
research Ruxolitinib found to cause eyelash growth: a case report
This study reports the first case of eyelash elongation and thickening in a patient with hypereosinophilic syndrome taking the Janus kinase inhibitor ruxolitinib.
research A Middle-Aged Man Presenting with a New Asymmetrical Poikilodematous Erythema on the Lateral Neck
This case report describes a middle-aged man with niacinamide-induced poikilodermatous flushing observed on the neck, established through clinical and dermatoscopic evaluation.
research Brimonidine Beyond a Single Specialty: Pharmacological Profile, Dermatologic Applications, and Advances in Drug Delivery Systems
This review highlights brimonidine’s potential as a dermatological agent, noting its ability to improve rosacea-related facial redness and its effectiveness in various other skin conditions due to its vasoconstrictive and anti-inflammatory actions, with minimal systemic absorption and a favorable safety profile for long-term use.
research 43225 Randomized study to assess the efficacy of a facial cosmetic product with nanoencapsulated cysteamine in women presenting melasma
In this study, a cosmetic product with nano encapsulated cysteamine plus sunscreen significantly improved melasma symptoms and quality of life in adult women over 84 days, compared to sunscreen alone, without any medically relevant intolerance.
research Design, Development, and Optimization of Spanlastics for Delivery of Rizatriptan Benzoate
This study investigated spanlastic nanovascular drug delivery systems and found that they can effectively enhance the transport and continuous release of medicines with small particle size, low polydispersity index, and satisfactory entrapment efficiency, showing potential as carriers for drug delivery.
research ODAC Votes No on IntraDose Injectible Cisplatin/Epinephrine Gel for Head and Neck Cancer
The committee unanimously voted against recommending approval of the injectable cisplatin/epinephrine gel IntraDose for certain head and neck cancer patients, citing insufficient clinical benefit and concerns about toxicity in this study.
research Icariside II inhibits gastric cancer progression by suppressing the Wnt/β-catenin signaling pathway
This study observed that Icariside II, an extract from Epimedium brevicornu Maxim, can inhibit the growth of gastric cancer in cell lines and mouse models by promoting apoptosis and suppressing the Wnt/β-catenin signaling pathway, with minimal toxicity to normal gastric cells.
research Finasteride 1 mg has no inhibitory effect on omeprazole metabolism in extensive and poor metabolizers for CYP2C19 in Japanese
This study concluded that finasteride 1 mg does not significantly affect the metabolism of omeprazole in young healthy Japanese male extensive or poor metabolizers for CYP2C19.
research Minoxidil
research Minoxidil
research Minoxidil
research Minoxidil
research Nanoemulgel: For Promising Topical and Systemic Delivery
This source describes the potential benefits of a nanoemulgel delivery system for enhancing the use of lipophilic drugs, improving patient compliance, and expanding treatment options for various conditions, including acne, arthritis-related inflammation, and Parkinson's disease, while also offering sunburn protection in cosmetic applications.
research Niosomes as a propitious carrier for topical drug delivery
This review discusses niosomes' increasing popularity in dermatology for topical drug delivery due to their ability to enhance drug penetration, provide sustained release, and carry various drugs, while reporting no new clinical findings.
research 72707 Effects of Oral Nicotinamide Mononucleotide (NMN) Supplementation on Hair: Influence of Fatigue on Treatment Outcomes
research Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
This review reports that nirmatrelvir-ritonavir has significant drug-drug interactions with many common dermatological medications, whereas molnupiravir may be an alternative therapy due to the absence of such interactions observed so far.
research Cholesterol and Phospholipid-free Multilamellar Niosomes Regulate Transdermal Permeation of a Hydrophobic Agent Potentially Administrated for Treating Diseases in Deep Hair Follicles
This study found that cholesterol- and phospholipid-free multilamellar niosomes improved skin deposition and targeted deeper hair follicles better than hydrophobic PLGA nanoparticles for transdermal drug delivery.
research Minoxidil
research Minoxidil
research Application of Acyzol in the Context of Zinc Deficiency and Perspectives
This article reviews the potential of Acyzol, a zinc-containing drug, to treat and prevent zinc deficiency conditions, but it reports no new clinical findings.
research Tamoxifen-induced androgenetic alopecia in a dialysis patient with sclerosing encapsulating peritonitis (SEP)
research Rizatriptan benzoate-loaded dissolving microneedle patch for management of acute migraine therapy
This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.
research Niosomes: A Novel Targeted Drug Delivery System
This review explores fundamental aspects of niosomes in drug delivery, including their structure, preparation methods, and factors influencing their formation, but it reports no new experimental results.
research Targeted skin delivery of topically applied drugs by optimised formulation design
This study found that nanoemulsions containing oleic acid or eucalyptol significantly enhanced the skin penetration of caffeine and naproxen compared to aqueous solutions, primarily by increasing solute diffusivity in the stratum corneum.