February 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Merkel cells stabilize nerve endings in the skin, and they change independently of each other.
70 citations,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
19 citations,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
February 2021 in “Current psychopharmacology” Pregnancy and nursing increase certain brain activities in rats, but these changes disappear when the babies are taken away.
47 citations,
December 2002 in “Journal of Neurochemistry” Progesterone boosts alcohol's effect on brain, finasteride counters it.
3 citations,
September 2020 in “Molecular Brain” The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
October 2023 in “Cytotherapy” Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.
April 2023 in “Journal of clinical and translational science”
25 citations,
August 2012 in “Acta Biomaterialia” Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
5 citations,
January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
Meis2 is essential for touch sensation and nerve function in mice.
10 citations,
March 2018 in “Chemosphere” Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
July 2019 in “Acta Scientiae Veterinariae” Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.
1 citations,
June 2023 in “Reproduction” Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
April 2020 in “Journal of chemical neuroanatomy” Researchers found a way to make rat hair follicle cells start turning into motor neuron-like cells, but couldn't fully turn them into working motor neurons.
The data suggests that dosing differences can help manage spasticity in patients with upper motor neuron dysfunction.
201 citations,
November 1964 in “Journal of neurophysiology” The cuneate nucleus has two main neuron types: relay neurons and interneurons.
1 citations,
November 2015 Dental pulp stem cells might not reliably become neurons.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
1 citations,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
237 citations,
December 2001 in “Urology” Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
115 citations,
May 2005 in “Brain Behavior and Immunity” Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
86 citations,
May 2002 in “Journal of comparative neurology” Nerve growth in mouse skin and hair follicles happens in stages and is closely linked to hair development.
83 citations,
September 2021 in “Advanced functional materials” The DNA hydrogel helps heal diabetic wounds by absorbing fluids, warming, sticking to tissue, killing bacteria, and aiding tissue and hair regrowth.
65 citations,
November 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
65 citations,
August 2013 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
52 citations,
July 2001 in “Molecular and cellular endocrinology” Activin A helps heal skin wounds and protects the brain after injury.
43 citations,
January 2016 in “Oxidative medicine and cellular longevity” THSG from a Chinese plant helps with aging and related diseases.
33 citations,
December 2010 in “Journal of Dermatological Science” Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
32 citations,
January 2014 in “Cells tissues organs” Hair follicle stem cells can help repair nerve and spinal cord injuries.