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We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Neurosteroids show promise for treating epilepsy and more research is needed.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Finasteride reduces movement issues in Parkinson's disease rats.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Hair growth and health are influenced by stress and hormones.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Using steroids can increase the risk of heart problems.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Finasteride may increase depression by reducing brain cell growth.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

The girl with autoimmune hair loss might regrow hair within a year, and treatments can help but not prevent recurrence; dermatologist referral and corticosteroids are recommended.

Gut flora changes could potentially indicate depression, but more research is needed.