64 citations,
January 2009 in “The International journal of developmental biology” Hair follicle stem cells are controlled by their surrounding environment.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
165 citations,
October 2013 in “Nature Communications” Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
43 citations,
July 2014 in “Experimental Dermatology” Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
28 citations,
January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders” Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
January 2016 in “Elsevier eBooks” The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
21 citations,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
4 citations,
March 2019 in “Experimental Biology and Medicine” Exposure to 50 Hz electromagnetic fields may help mice grow hair faster.
August 2024 in “Indian Journal of Skin Allergy” Stem-cell therapy shows promise for skin conditions but needs more research.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
44 citations,
November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
35 citations,
January 2017 in “Journal of Dermatological Science” Stress can cause early aging in certain skin cells, leading to problems with hair growth.
16 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
9 citations,
July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
5 citations,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
April 2023 in “Dentistry” Baby teeth stem cells can potentially grow organs and treat diseases.
57 citations,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
30 citations,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
13 citations,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
4 citations,
May 2021 in “Biomedicines” Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
28 citations,
October 2013 in “Cornea” Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.