May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study identified six molecules from herbal extracts that effectively bind to 5-alpha reductase (5-AR), with Jomogenin showing high binding stability when encapsulated in lipid nanoparticles, suggesting their potential for further experimental analysis to aid hair follicle growth.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this computational study, researchers identified six phytochemicals, including Jamogenin, that effectively bind to the enzyme 5-AR, potentially promoting hair growth, and found that encapsulating Jamogenin in lipid nanoparticles enhances its stability.
July 2024 in “Journal of Eastern – Western Pharmacology and Pharmacy” This study found that Tribulus terrestris L. extract promoted significant hair growth and reduced skin inflammation in Wistar rats, while Urtica cannabina extract, Glycyrrhiza glabra extract, and Tribulus terrestris L. extract all led to uniform hair growth over 28 days compared to other tested extracts.
February 2024 in “Cosmetics” In this study, researchers developed a novel platform for discovering potential hair loss inhibitors by investigating the testosterone/dihydrotestosterone biosynthetic pathway and its regulation through biochemical mechanisms involving 17β-HSD and 3β-HSD, combined with medicinal plant extracts.
January 2018 in “Turkiye Klinikleri Journal of Dermatology” This study identified the most common plants in hair cosmetics, like shampoos and dyes, with Rosmarinus officinalis L. and Lawsonia inermis L. leading, to serve as a reference for future research and healthcare professionals.
September 1997 in “Bulletin of the history of medicine” This review discusses the potential for discovering new drugs in ancient and medieval European texts and reports no new clinical research, emphasizing the need for scientific exploration of historical medicinal knowledge.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
July 2019 in “Technology audit and production reserves” This research discusses the formulation of probiotic gel shampoos with whey peptides and plant extracts, highlighting their potential effectiveness and market feasibility in Ukraine.
September 2018 in “Central Asian journal of medical sciences (Print)” This study found that Urticadioica L ethanol extracts enhanced hair growth and reduced catagen transition in human hair follicles in an ex vivo organ culture model.
March 2018 in “Farmacevtičnij časopis” In this study, researchers developed an optimized production process for the herbal tincture "Stimufit," intended for topical use in treating telogen alopecia, using 40% ethanol and a specific extraction method.
This study reported that a shampoo containing alcoholic extract of Urtica urens L. was effective in reducing hair loss by over 50% without causing skin irritability.
January 2015 in “Farmatsevtychnyĭ zhurnal” This research discusses the development of a complex tincture for telogen effluvium using nettle, sage, and chestnut leaves, but provides no new clinical results.
In a laboratory setting, this study reported that the n-butanol fraction of Urtica laetevirens Maxim. water extracts significantly inhibited 5α-reductase activity.
January 2009 in “Lishizhen Medicine and Materia Medica Research” The researchers reported that the aqueous extract of Urtica fissa E.Pritz inhibited 5α-reductase activity in vitro.
March 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This article discusses various synthetic and herbal treatments for alopecia, noting limited effectiveness and associated side effects of synthetic options, and reports no new clinical results.
69 citations
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July 1997 in “Der Urologe” This study found that PRO 160/120 and Finasteride showed similar effectiveness in improving urinary symptoms and quality of life in patients with benign prostatic hyperplasia over 48 weeks.
67 citations
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February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.
54 citations
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September 2002 in “Annals of Pharmacotherapy” This review discusses various herbal therapies, such as Serenoa repens and Pygeum africanum, for treating benign prostatic hyperplasia, noting their potential but highlighting unresolved questions about their efficacy and safety.
32 citations
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January 2012 in “Chinese Medicine” In this study, a hydro-alcoholic extract of Urtica dioica demonstrated in vitro antioxidant activity, potentially linked to its ferulic acid content.
14 citations
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June 2014 in “World Journal of Urology” This study found that the herbal combination PRO 160/120 significantly improved nocturnal voiding frequency in patients with moderate-to-severe LUTS/BPH compared to placebo, with similar effectiveness to tamsulosin and finasteride.
14 citations
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January 2014 in “Tropical Journal of Pharmaceutical Research” In this study, a hydroalcoholic extract of Urtica dioica L. showed potential for use as an adjunct topical treatment for tinea corporis in guinea pigs infected with Microsporum canis.
4 citations
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October 2013 in “Botanics Targets and Therapy” In this animal study, a herbal preparation demonstrated moderate anti-inflammatory and immunomodulating properties, suggesting its potential usefulness for preventing and treating alopecia.
3 citations
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January 2019 in “Therapeutic advances in urology” This review concluded that WS PRO 160 I 120 mg, a herbal preparation, may be an effective and safer alternative to standard drugs for treating lower urinary tract symptoms in men with benign prostatic hyperplasia.
3 citations
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July 2018 in “DergiPark (Istanbul University)” This article reviews the usage of medicinal plants for treating certain conditions in European Turkey, detailing the plants' parts, preparatory methods, and traditional therapeutic applications but reports no new experimental results.
2 citations
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December 2021 in “ScienceRise” This study identified optimal parameters for extracting oil from Urtica dioica roots to maximize phytosterol content, using corn oil and a 1:5 raw material-extract ratio over a 6-hour maceration period.
December 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses three herbal plants commonly used for hair growth support and reports no new clinical results; the authors suggest these herbs may help restore hair health.
This study found that the hydroalcoholic extract of Urtica dioica L. demonstrated some clinical efficacy in reducing lesion severity in guinea pigs with Microsporum canis infections, suggesting potential as a supplementary topical treatment for tinea corporis.
January 2009 in “Elsevier eBooks” This chapter reviews botanical treatments for polycystic ovary syndrome, discussing potential benefits but presenting no new clinical results; it emphasizes the use of botanicals for managing symptoms like anovulation, insulin resistance, and inflammation.
February 2023 in “Current Pharmaceutical Design” This review explores medicinal plants as potential treatments for hair loss, suggesting their promise due to anti-inflammatory and antioxidant properties, but reports no new clinical results.
December 2011 in “Asia-Pacific biotech news” This collection of research news highlights various scientific advancements, including discoveries in anti-cancer compounds, new cell types that boost immunity, and a potential Parkinson's breakthrough in Australia, among others from China, India, Korea, Singapore, and Thailand.