The Substantiation of Plant Raw Materials Ratio and Determination of Raw Materials Technological Parameters in the Development of Complex Tincture for the Telogen Effluvium Treatment

The document details the creation of a tincture designed to treat telogen effluvium, focusing on the optimal composition and ratio of medicinal plant raw materials (MPRM) like nettle leaves, sage leaves, and horse chestnut leaves. The study aimed to combine these plants in a way that leverages their biologically active substances to combat the disease's pathogenesis. The optimal ratio was found to be 5:3:2 (nettle:sage:horse chestnut), and technological parameters such as mass loss during drying and porosity were analyzed to facilitate the industrial production of the tincture. The findings are intended to guide the development of extraction processes and technological regulations for this phytotherapeutic product.