Study on Inhibitory Effect of Urtica Laetevirens Maxim. Extract on 5α-Reductase
January 2014
New to Finasteride? There is a guide in the encyclopedia. Read the guide → Studysummary In a laboratory setting, this study reported that the n-butanol fraction of Urtica laetevirens Maxim. water extracts significantly inhibited 5α-reductase activity.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study investigated the inhibitory effects of Urtica laetevirens Maxim. extract on 5α-reductase using an in vitro model. The reactive system included 5α-reductase from male rat livers, testosterone, and NADPH. High-performance liquid chromatography (HPLC) measured testosterone concentration changes to assess 5α-reductase activity. The n-butanol fraction of the water extracts of Urtica laetevirens Maxim. significantly inhibited 5α-reductase activity, with finasteride serving as a positive control.
