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This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.

This study found that recombinant murine IL-36α increased the number of regenerated hair follicles and accelerated wound healing in a mouse model of wound-induced hair follicle neogenesis.

This case report describes an 80-year-old patient whose scalp wound healed by secondary intention, with unexpected hair regrowth observed at 180 days, suggesting hair neogenesis is possible even in older adults.

This review discusses factors affecting wound-induced hair neogenesis in mice and reports no new results; it aims to facilitate meaningful comparisons of experiments across different laboratories.

This study found that activin A signaling is crucial for hair follicle neogenesis in human dermal papilla 3D cultures combined with mouse epidermal cells.

This study found that OVOL1-regulated genes, particularly Fst and SFRP1, significantly affect the hair-inducing capacity of neonatal mouse dermal cells.

This document includes a brief professional profile of Dr. Ralf Paus but presents no research findings or study results.

This paper proposes that GDNF signaling may enhance skin regeneration and hair follicle formation by influencing dermal fibroblast differentiation, particularly following injury.

This study found that altering mechanical signals in mouse wounds, particularly through FAK inhibition, increased hair regeneration by modulating wound stiffness and gene expression linked to tissue regeneration.

In this study, Huoxue Bushen Mixture was associated with increased blood vessel formation and VEGF expression in mice hair follicles, suggesting it may enhance hair growth.

This study investigated the role of the glycoprotein Thy-1 in hypertrophic scar formation using a murine model, finding that Thy-1 knockdown reduced scar size and encouraged functional regeneration by influencing the p38MAPK signaling pathway under high-tension conditions.

This review explores the mechanisms of wound-induced hair follicle neogenesis in mice, discussing its potential to inform precision therapies for alopecia and scarless wound healing, but reports no new clinical results.

This study used single-cell RNA sequencing to explore the cellular differences between small and large wound tissues during the hair follicle regeneration stage, revealing variations in keratinocyte subpopulations and extracellular matrix interactions associated with wound size.

This review discusses wound‐induced hair follicle neogenesis and its potential for developing therapies for scar formation, but reports no new clinical results.

TGF-β signaling is essential for hair follicle regeneration during wound healing.

This review explores emerging therapies for hair regrowth, highlighting two strategies: hair follicle neogenesis and Wnt/B-catenin pathway modulation, which show promise for treating alopecia by potentially offering more effective options than existing treatments.

This study found that the peptide TSN6 increased epidermal thickness and promoted hair follicle formation in dermal–epidermal composites grafted onto nude mice, with TSN6-treated composites showing more hair follicles and retained grafts compared to control groups.

This review discusses the mechanisms regulating wound-induced hair-follicle neogenesis and highlights potential treatments, like Wnt signaling activators, for enhancing this process in humans, yet reports no new clinical results.

TGF-β signaling is essential for new hair growth after wounds.

Bioactive peptides improve graft survival and new hair growth.

A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.

In this study, researchers found that both Wnt/β-catenin and Hedgehog signaling pathways must be activated in wound fibroblasts to promote hair follicle neogenesis in mice, suggesting these pathways are crucial for regenerative healing strategies.

This study provides a detailed analysis of cell subpopulations in a mouse model of wound-induced hair follicle regeneration, revealing specific cellular dynamics and heterogeneity that may influence hair follicle neogenesis.

This review discusses the potential of the hair follicle dermis to direct hair development and explores concepts related to hair growth and androgenetic alopecia, without reporting new clinical results.

In this study, KY19382 was observed to promote hair regeneration and de novo hair follicle formation in mice by activating Wnt/β-catenin signaling, suggesting its potential as a therapeutic for alopecia.

This study observed that mice treated with mrIL-36α showed differences in wound-induced hair neogenesis compared to those treated with PBS, indicating a potential role of mrIL-36α in hair growth after skin injury.

African spiny mice can regenerate skin and hair after wounds due to specific tissue mechanics.

This study found that extracellular factors from a specific developmental stage can promote hair follicle neogenesis in adult skin by facilitating interactions between fibroblasts and keratinocytes.

This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.