45 citations
,
January 2021 in “Drug Delivery” In this study, researchers developed a biomimetic anti-inflammatory nanosystem (MM-CEP/NLCs) that significantly reduced the severity of acute lung injury in vivo by targeting and accumulating in lung inflammation sites, showcasing its potential for treating inflammation.
10 citations
,
July 2023 in “Pharmaceuticals” This study explored the wound healing potential of a natural marine soft coral-derived nanoparticle-based gel in a diabetic excision wound model, finding it effectively regulates proinflammatory cytokines and inhibits enzymes related to wound healing.
150 citations
,
November 2007 in “The Journal of Clinical Endocrinology and Metabolism” This study determined that nonclassical congenital adrenal hyperplasia has a 2.2% prevalence among hyperandrogenic women in Spain, with basal serum 17-hydroxyprogesterone showing excellent diagnostic performance.
1 citations
,
March 2023 in “International Wound Journal” This article reviewed a study suggesting that CCN1 secreted by human adipose-derived stem cells may enhance wound healing, although the authors note limitations such as small sample size and incomplete evaluation of wound healing processes.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study discovered a novel mechanism by which germ stem cells exit their niche in C. elegans, involving thin membranous protrusions from adjacent somatic gonad cells.
11 citations
,
June 2025 in “Polymers” This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.
This study found that spearmint tea reduced testosterone levels and improved self-reported hirsutism in women with PCOS, but did not significantly change objective hirsutism scores during the 30-day trial.
8 citations
,
May 2024 in “ACS Applied Materials & Interfaces” This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.
1 citations
,
September 2025 in “Scientific Reports” This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.
This study found that activating BMP signaling in rodent and primate models significantly promotes nail and digit regeneration after amputation by enhancing the role of specific nail stem cells, though extreme proximal amputation only permitted partial regeneration without bone reconstruction.
October 2024 in “Asian Pacific Journal of Cancer Prevention” This study found that methanolic extract from Cnicus Benedictus leaves inhibits the growth of human cervical cancer cells in vitro and selectively targets cancer cells over normal cells, suggesting potential safety in its efficacy.
8 citations
,
April 2017 in “American Journal of Dermatopathology” In this study, nail matrix pathology in a patient with Cronkhite–Canada Syndrome revealed matrix hypergranulosis, suggesting that an inflammatory process may play a key role in the condition's pathogenesis.
24 citations
,
February 2015 in “Experimental Cell Research” This study found that overexpression of the transcription factor NFIC may enhance the proliferation and differentiation of stem cells from the apical papilla, suggesting its potential role in dentin/root regeneration.
21 citations
,
January 1999 in “Molecular and Cellular Biochemistry” Niacin deficiency makes rats more sensitive to cancer-causing chemicals.
January 2023 in “Indian dermatology online journal” This case report describes a novel NECTIN4 gene mutation linked to ED-syndactyly syndrome 1 in a young girl, contributing to the understanding of this rare ectodermal dysplasia.
87 citations
,
July 2009 in “Journal of Cell Science” The researchers found that corneodesmosin is crucial for maintaining skin barrier integrity and hair follicle architecture in mice, with its deletion leading to severe skin and hair abnormalities.
41 citations
,
July 2016 in “Journal of Investigative Dermatology” This study identified molecular differences between dysplastic nevi and common melanocytic nevi, including altered keratinocyte differentiation, increased hair follicle-related molecule expression, and distinct immune microenvironment characteristics in dysplastic nevi.
10 citations
,
August 2024 in “ACS Omega” This review discusses the use of nanomaterials in cosmetics, highlighting their benefits like enhanced stability and skin penetration, while also noting potential health risks and the role of natural ingredients in formulations.
June 2025 in “Journal of General-Procedural Dermatology & Venereology Indonesia” In this study, a 14-year-old boy with nevus sebaceous on his scalp underwent a three-stage serial excision, resulting in complete lesion removal with minimal scarring and no recurrence after six months.
11 citations
,
August 2019 in “Journal of Molecular Histology” This study found that upregulation of NFIC may enhance proliferation and osteogenic/cementogenic differentiation in rat dental follicle cells.
50 citations
,
March 2018 in “BMC Genomics” This study expands knowledge of non-coding RNAs in goats and other mammals, enhancing understanding of their roles in hair follicle growth and regression.
October 2025 in “Cell Death and Disease” In this study, researchers developed two novel mouse models to investigate how CD271 deletion in keratinocytes affects skin homeostasis, finding that it leads to changes resembling dysplastic skin conditions with immune cell recruitment and inflammatory cytokine release.
43 citations
,
February 2020 in “Clinica chimica acta” This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.
15 citations
,
November 2020 in “International Journal of Molecular Sciences” This study found that multi-walled carbon nanotubes promoted root hair growth in certain plants, with results indicating they modulate nitric oxide and ethylene pathways crucial to this development.
August 2020 in “Research Square (Research Square)” This study found that nanovesicles derived from ReNcell VM cells promoted hair growth in mice by activating the Wnt/β-catenin signaling pathway, suggesting they may serve as an alternative to extracellular vesicles for hair growth therapy.
4 citations
,
December 2013 in “Acupuncture and related therapies” This review summarizes the potential of N-acetyl-cysteine in managing diseases linked to redox imbalance, discussing its effects from cellular mechanisms to clinical applications, though further research is suggested for broader use.
56 citations
,
December 2011 in “Steroids” This review discusses the genetics and variable phenotypic expression of nonclassic congenital adrenal hyperplasia, and reports no new clinical results; the authors call for further research on long-term health impacts and treatment strategies.
30 citations
,
June 2019 in “Frontiers in Endocrinology” This article discusses the challenges in diagnosing non-classical congenital adrenal hyperplasia and emphasizes personalized treatment approaches, reporting no new clinical results.
6 citations
,
June 2025 in “Nano Biomedicine and Engineering” This source reports on advances in stimulus-responsive nanoparticle-based PROTACs (nano-PROTACs), which aim to overcome existing challenges like poor cell permeability and systemic off-target effects by enabling controlled protein degradation through endogenous or exogenous stimuli, potentially enhancing therapeutic efficacy and reducing toxicity.
Nonlinear artificial neural networks are better at identifying different types of animal hair than linear ones.