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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Uterine transplants for transgender women are feasible but need more research.

Different processes create patterns in skin and things like hair and feathers.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

Passiflora incarnata may help with anxiety but has risks and drug interactions. There's a genetic link between Fragile X Syndrome and Autism Spectrum Disorder. 6.7% of urine cultures showed hospital-acquired urinary tract infections. Children used screens more during COVID-19, causing various health complaints. Autism Spectrum Disorder is often underdiagnosed in females. Dissociative disorders in childhood sexual abuse victims are more common in males. Most pregnant teenagers are not dissatisfied with their body image but worry about weight. Diagnosing tuberculosis after knee surgery is challenging due to non-specific symptoms. Post-COVID-19 syndrome is more common in older, severely affected patients. Psychiatrists should be part of pain management teams due to the psychological aspects of pain.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Prolactin affects when mice shed and grow hair.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Gender identity can be more diverse than just male or female.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Prolactin affects when mice shed and grow hair.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.