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This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.

This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.

In this study, dermal papilla cell-derived exosomes accelerated hair follicle growth in mice, suggesting potential for treating hair loss by modulating key signaling pathways.

This study found that ethosomal carriers enhanced dermal and transdermal drug delivery more effectively than classic liposomes, improving delivery to deep skin layers and showing potential for treating conditions like herpes labialis and diabetes.

This upcoming clinical trial at Shenzhen People's Hospital will explore the safety and efficacy of human umbilical cord mesenchymal stem cell-derived small extracellular vesicles as a treatment for androgenetic alopecia in young men, comparing them to minoxidil. Results are not reported yet.

This study found that Limelight (CB-EVs) exosomes significantly promoted hair elongation ex vivo without cytotoxicity, suggesting potential as a safe and effective hair growth therapy.

This study found that cubosomes combined with dissolving microneedles enhanced transdermal penetration and hair growth efficacy of beta-sitosterol for treating alopecia.

This review discusses the use of nanocarrier technology in functional cosmetics to enhance skin penetration, increase ingredient stability, and allow codelivery of active ingredients, without reporting new clinical results.

The study observed that cell spheres formed from mesenchymal cells of newborn mice skin exhibited upregulation of markers linked to hair follicle regeneration, suggesting a potential hibernation-like state for maintaining viability.

This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.

This study found that nanostructured lipid carriers enabled effective follicular delivery and accumulation of anti-hair loss drugs like dutasteride in mice, suggesting potential for reduced dosage frequency.

In this study, researchers developed a microfluidics-based method for creating uniform, size-controlled stem cell spheroids that enhance osteogenic differentiation when encapsulated in alginate-RGD microgels.

This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.

This study found that VEGF expression and microvessel density in hair follicles of Liaoning cashmere goats follow a bimodal pattern correlated with hair development throughout the year.

In this study, microneedles combined with finasteride nanostructured lipid carriers (FIN-NLC-MNs) were found to enhance skin penetration and specifically target hair follicles, promoting hair growth and gene regulation in androgenetic alopecia.

This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.

This study found that arginine vasotocin is evolutionarily conserved across diverse taxa and may play roles in neuroendocrine, immune, and stress signaling, with potential antimicrobial applications.

In this study, N-MXD (minoxidil nanoparticles) was shown to deliver more drug into hair bulbs and enhance IGF-1 and VEGF levels more effectively than commercial formulations, resulting in higher therapeutic efficiency for hair growth in C57BL/6 mice.

This study discovered a conserved "fiber-like-motif" of melanosomes aligned in hair across various mammalian species, shedding light on the internal structure that influences hair's thermal and mechanical properties.

This study highlights the potential of nanofibers in cosmeceuticals, reporting that nanofiber facial masks outperform regular masks in cleansing, and notes their exploratory use in anti-acne patches for enhanced acne management.

This study suggests that IT PEP injection may have beneficial effects after spinal cord injury, but additional research is necessary to better understand and optimize its clinical application.

This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.

This study suggests that using nanostructured lipid carriers may improve the targeting of 17-α-estradiol in treating alopecia by improving skin penetration and stability.

This study observed that topical oligonucleotide penetration in mouse skin involves a follicular route, suggesting potential suitability for targeting hair follicle-related structures.

In this study, hair follicle neural crest stem cell-derived exosomes, especially those overexpressing miR-214-3p, significantly promoted axon extension and nerve regeneration in both in vitro and in vivo models, suggesting a promising therapeutic strategy for peripheral nerve injuries.

In this study, exosomes were identified as influential in skin biology, demonstrating potential in accelerating wound healing by modulating inflammation and enhancing tissue regeneration, though their use remains primarily cosmetic pending FDA approval.

This study suggests that common proteomic changes, including the expression of the protein S100A6, may occur during the expansion of AD-MSC from different donors.

This study found that exosomes derived from human umbilical cord mesenchymal stem cells enhanced the growth of human hair dermal papilla cells by promoting cell cycle progression and activating PI3K and Akt-dependent pathways, indicating potential for hair loss treatment.