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Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

γδ T cells help with hair growth during wound healing in mice.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Manatee whiskers are specially adapted for touch in water.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Both gene and non-gene areas of DNA evolved to make some mammals hairless.

Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Innovative methods are reducing animal testing and improving biomedical research.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Balanced vitamin D levels are crucial to delay aging and prevent related diseases.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Fluridil promotes hair growth safely and effectively for androgenetic alopecia.

Human skin can make serotonin and melatonin, which help protect and maintain it.