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This review explores the impact of COVID-19 on skin appendages beyond COVID-toes, highlighting hair and nail disorders in affected individuals, but provides no new clinical results.

This review focuses on the various skin symptoms associated with COVID-19 but reports no new clinical findings.

This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.

This case report describes a 23-year-old male patient with nail discoloration that may be associated with COVID-19, suggesting possible microvascular damage.

This review found that infliximab, golimumab, and some forms of radiotherapy significantly improved nail psoriasis compared to controls, although they could have serious adverse effects and are not commonly used specifically for nail issues.

This review summarizes recent findings on FOXN1's essential role in thymus and skin biology and discusses emerging therapeutic approaches for immune disorders with athymia, but reports no new clinical results.

This is the first report of the FOXN1 p.R255X mutation from India, demonstrating the global spread of this genetic mutation previously found only in an Italian community.

This study reports two siblings with severe combined immunodeficiency due to a mutation in the FOXN1 gene, characterized by T-cell immunodeficiency, alopecia totalis, and nail dystrophy.

This study highlights that prolonged voriconazole use is linked to an increased risk of aggressive cutaneous malignancies like squamous cell carcinoma, necessitating careful monitoring of drug levels to manage adverse effects.

This article reviews the cutaneous reactions and characteristic skin changes associated with chemotherapy, radiation therapy, and new targeted cancer treatments, reporting no new clinical results.

This study found that pulse corticosteroids effectively induce hair regrowth in alopecia areata, with betamethasone showing higher efficacy but more side effects, and treatment success varying depending on age, onset time, and disease type.

This article suggests that nail abnormalities might occur temporarily after COVID-19 vaccination, but they are self-limiting and should not deter individuals from getting vaccinated.

This study found that patients who recovered from COVID-19 experienced various skin, hair, and nail issues, with hair shedding being more common in those with moderate to severe cases.

This study reports that the Pfizer-BioNTech COVID-19 vaccine showed 52% protection against COVID-19 after the first dose and 95% after the second in phase 3 trials.

This study observed that PAI-2 is consistently expressed in differentiating cells of murine hair and nail, suggesting it may function as a marker of differentiation and possibly protect against premature cell death.

In this study, Flii overexpression in mice enhanced fingertip regeneration and nail formation after both distal and proximal amputations, suggesting a role in digit and hair follicle regeneration possibly involving Wnt signaling.

In this study, three patients with alopecia areata exhibited spotty absence of the whiteness of their nail lunulae, potentially due to defects in the matrical epithelium.

This review found that both oral and topical soy-based products showed positive effects on various skin-related outcomes, including aging signs and skin barrier function, but topical applications were more likely to improve skin barrier status compared to oral supplementation.

This review summarizes existing knowledge on the role of FOXN1 as a key regulator of thymic epithelial cell lineage and function, reporting no new experimental results.

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

The systematic review reports an association between Beau’s lines and COVID-19 infection or vaccination, observing variability in onset and resolution times, and suggesting these nail disorders might indicate previous severe infection or vaccination, as well as potentially signify long COVID-19 syndrome.

This study reports that COVID-19 can trigger various dermatological autoimmune and autoinflammatory diseases, highlighting the need for clinicians to consider these potential connections during the pandemic.

This review explores the role of FGF signaling in hair follicle development and highlights its potential as a new therapeutic target for hair loss, which could surpass existing treatments in terms of efficacy and safety.

This study found that DPCP immunotherapy effectively treats alopecia areata, identifying factors that influence treatment response and patient satisfaction, which may aid in standardizing the treatment for improved outcomes.

This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.

This study found that alopecia areata patients consider more than 20% scalp hair loss, chronic duration, and involvement of additional body hair as indicators of severe disease impacting quality of life.

In this study, platelet-rich plasma therapy was observed to provide better improvement in hair regrowth for alopecia areata patients than intralesional triamcinolone acetonide, as measured by lower SALT scores.

This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.

Herman Bierens had a successful career in econometrics, contributed to education, and plans to continue research after retirement.

In this study, dermoscopic examination of COVID-19 patients revealed significant microvascular changes in the proximal nailfold, such as avascular areas and disorganized capillary architecture, compared to healthy controls, with some regression of these changes observed over time.