7 citations
,
May 2014 in “Clinical practice” This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.
39 citations
,
January 2019 in “Journal of Dermatological Treatment” This review found topical ketoconazole to be highly effective against Malassezia-related skin conditions, though other treatments may outperform it for Tinea and Candida infections.
1 citations
,
August 2025 in “Journal of Neonatal Surgery” This study evaluated a new nanogel formulation containing Ciclopirox Olamine for treating cutaneous candidiasis, finding that the optimized version offered improved skin penetration, sustained drug release, and effective antifungal action against Candida albicans compared to conventional treatment.
November 2022 in “Journal of Education, Health and Sport” This review discusses the current understanding of the skin microbiome's potential influence on alopecia areata and emphasizes the need for further study, reporting no new experimental results.
January 2013 in “Japan labor review” This study quantified relationships among various occupations in Japan, enabling comparisons with vocational aptitude test results using new numerical criteria developed from analysis of over three million survey panels.
9 citations
,
December 2017 in “The Journal of Allergy and Clinical Immunology” This review discusses the evolution of alopecia areata treatments towards more targeted therapies and reports no new clinical results, emphasizing cooperation between clinicians and scientists in understanding the disease's pathophysiology.
4 citations
,
November 2023 in “Frontiers in immunology” In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.
3 citations
,
October 2021 in “Letters in Applied NanoBioScience” This article explores the integration of nanotechnology and cosmetics, highlighting the development of cosmeceuticals targeting issues such as wrinkling, hyperpigmentation, and skin dehydration, while also reviewing cosmetic history and types of nanotechnology by particle size.
1 citations
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April 2025 in “Pediatria i Medycyna Rodzinna” This research re-analyzed single-cell gene expression data from a mouse model, confirming that certain genes involved in the EDA-EDAR and WNT pathways are crucial for skin appendage development, suggesting that their restoration may mitigate the effects of hypohidrotic ectodermal dysplasia in children.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.
October 2023 in “Case reports in dermatological medicine” In this case report, a 45-year-old Jordanian woman was diagnosed with Clouston syndrome, an autosomal-dominant disorder characterized by alopecia and nail dystrophy due to a mutation in the GJB6 gene, though she lacked the typical palmoplantar keratoderma.
38 citations
,
February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
17 citations
,
January 2010 in “Acta Dermato Venereologica” This report details a case of a 43-year-old woman developing yellowish papular eruptions alongside typical acneiform skin reactions on her cheeks and chest following a switch from cetuximab to panitumumab treatment.
1 citations
,
December 2024 in “Indian Dermatology Online Journal” This research notes that biologics and small molecules are effective for treating nail psoriasis and alopecia areata, albeit with precautions for adverse events, but no clinical trials have been published for their use in treating nail lichen planus and atopic dermatitis.
1 citations
,
January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
August 2024 in “Journal of the American Academy of Dermatology” Nail color change might be an early sign of skin pigmentation from minocycline.
This article reviews the history and characteristics of the rare nude phenotype SCID, primarily distinguished by severe T cell immunodeficiency and notable skin and hair abnormalities, but reports no new clinical findings.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study revealed that BMP5 in onychofibroblasts may play a key role in the differentiation of nail matrix keratinocytes, highlighting transcriptional similarities between nail and hair structures.
79 citations
,
December 1999 in “Mechanisms of Development” Whn is crucial for hair growth in certain areas by controlling a specific gene.
February 2026 in “Journal of Clinical Medicine” In this narrative review, researchers found preliminary evidence suggesting that minoxidil, both topical and oral, may enhance nail growth and improve nail strength and appearance, though more extensive studies are needed to confirm its efficacy and safety for this off-label use.
111 citations
,
November 2007 in “Clinics in Dermatology” This article discusses the histologic features of psoriasis, including psoriasiform epidermal hyperplasia and neutrophilic involvement, but reports no new clinical findings.
86 citations
,
October 2005 in “Experimental Dermatology” This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.
67 citations
,
September 2003 in “Journal of cutaneous pathology” This review discusses the various skin manifestations associated with end-stage renal disease and their potential causes but reports no new clinical findings; the authors emphasize pruritus as a significant condition.
30 citations
,
January 2021 in “Journal of Clinical Immunology” This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.
30 citations
,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the effects of thyroid hormone on the skin and explores the potential for using it to treat skin diseases, but reports no new clinical results.
27 citations
,
July 2015 in “International Journal of Dermatology” This study found that skin disorders are prevalent among elderly individuals and are often associated with underlying systemic diseases.
22 citations
,
March 2021 in “Journal of Cutaneous Medicine and Surgery” This review discusses the integration of ultrasound in dermatology for improved lesion visualization and diagnosis, highlighting recent technological advancements like handheld devices and high-frequency probes, and reports no clinical results.
19 citations
,
January 2018 in “Scientific Reports” This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.
18 citations
,
January 2017 in “Postępy Dermatologii i Alergologii” This review discusses the adverse skin effects of EGFR inhibitors used in cancer treatment, exploring their mechanisms and offering strategies for prevention and management, but reports no new experimental findings.
17 citations
,
June 2017 in “Gene” This is the first report of the FOXN1 p.R255X mutation from India, demonstrating the global spread of this genetic mutation previously found only in an Italian community.