Minoxidil Beyond Hair: A Comprehensive Review of Its Effects on Nail Growth

The review examines the potential of minoxidil, commonly used for hair growth, to enhance nail growth. It highlights studies showing that both topical and oral minoxidil can significantly increase nail growth rates, with oral minoxidil at 2.5 mg showing over a 50% increase. The drug's mechanisms include vasodilation, angiogenesis, and stimulation of cell proliferation, which benefit the nail matrix. While promising for conditions like yellow nail syndrome, the evidence is preliminary, based on small studies. The review calls for larger trials to confirm efficacy and safety, but minoxidil's low cost and availability make it a viable option for nail disorders.