December 2024 in “European Journal of Dermatology” In this study, oral minoxidil treatment at 2.5 mg/day significantly increased nail growth speed by 50.7% and hair growth speed by 35.9% in healthy adult men, while also increasing heart rate but not affecting blood pressure.
November 2024 in “Skin Health and Disease” This review suggests that while minoxidil is effective in promoting hair growth, its precise mechanism remains unclear, and it may have emerging applications in treating various dermatological conditions.
September 2023 in “Journal of Cosmetic Dermatology” This study concluded that topical minoxidil could effectively accelerate nail growth in both healthy individuals and those with nail disorders, though the regimen might differ across these groups.
1 citations
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May 2023 in “Journal of the European Academy of Dermatology and Venereology” In this retrospective study, the authors explored the use of minoxidil and vitamin E for treating nail growth disorders, but no specific outcomes or results are reported in the abstract.
February 2023 in “International Journal of Dermatology” This correspondence discusses the effects of oral minoxidil on nails but does not present new research findings.
16 citations
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June 2021 in “Journal of Dermatological Treatment” This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.
4 citations
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March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
117 citations
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August 2019 in “Drug Design Development and Therapy” This review article provides an updated overview of the pharmacology, mechanism of action, clinical efficacy, and adverse events associated with topical minoxidil, a widely used treatment for androgenetic alopecia and other hair loss conditions, while noting that its exact mechanism is still not fully understood.
8 citations
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April 2017 in “International Journal of Dermatology” This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.
152 citations
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April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
192 citations
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March 1998 in “British Journal of Dermatology” This study found that minoxidil significantly increases VEGF mRNA and protein expression in dermal papilla cells, suggesting a role in enhancing hair follicle vascularization in androgenetic alopecia.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
57 citations
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January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
17 citations
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May 1975 in “Clinical Pharmacology & Therapeutics” 
90 citations
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May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
