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Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

Getting insurance to cover the hair loss treatment tofacitinib is hard because it's not officially approved for that use.

Using old drugs for new uses can help treat rare immune deficiencies.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

DNMT3A is crucial for healthy skin and hair growth.

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Both induced and spontaneous AA lymphocytes can cause alopecia areata in mice.

Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.

There's a growing resistance to the antibiotic mupirocin in children's skin infections caused by MRSA in New York.

Treatment with biologic agents can significantly improve psoriasis symptoms, and blood biomarkers could potentially predict individual patient's response to treatment.

Finasteride for hair loss may increase the risk of certain cancers and has side effects; better regulation and education on its use are needed.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Targeted cancer therapies often cause serious skin problems that need careful management.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.