research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
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150-180 / 1000+ resultsresearch A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle
A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
research Genetic Control and Involvement in Hair Fiber Traits
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion in Mice Through Enhancer Dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in Hair Follicle Morphogenesis and Homeostasis
SGK3 is essential for proper hair growth and health.
research A Pair of Transmembrane Receptors Essential for the Retention and Pigmentation of Hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Whole-Genome SNP Genotyping Mapped a Novel Locus for Hereditary Hypotrichosis on Chromosome 2q31.1–q32.2
Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.
research Regulation of the Human Hair Cycle
The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
research Autosomal Recessive Hypotrichosis Simplex With Woolly Hair: A Report of a New Family
Two siblings were found to have a genetic condition causing progressive hair loss and woolly hair, which may often be misdiagnosed.
research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
research Recent Updates on Wnt Signaling Modulators: A Patent Review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Thyroid Hormone Action on Skin
Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
research Hair Loss in Children: Diagnosis and Treatment
The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.
research Potential Therapeutic Uses of Thyroid Hormone
Thyroid hormone may be useful for treating various skin conditions and needs more research.
research The Proteomic Profile of Hair Damage
Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
research The Naked Truth: Sphynx and Devon Rex Cat Breed Mutations in KRT71
Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.
research Odd-Looking Hair and Progressive Alopecia in Mother and Son
Mother and son diagnosed with a rare genetic hair loss condition with no effective treatment.
research Commonly Associated Disorders With Complete Scalp Alopecia in Early Childhood: A Review
Six genetic conditions are often linked to complete scalp hair loss in children.
research Clinical Course of the First Japanese Family with Marie Unna Hereditary Hypotrichosis: A Follow-Up Report
The first Japanese family with Marie Unna hereditary hypotrichosis showed hair condition improvement in a child and highlighted the risk of misdiagnosis.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research An Immune Regulatory CCT Repeat Containing Oligodeoxynucleotide Capable of Causing Hair Loss in Male Mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research Evaluation of the Relationship Between Androgenetic Alopecia and Blood Groups and Rhesus Factor
No link between hair loss and blood groups or Rhesus factor.
research Two Females With Hair Loss
A mother and daughter have a rare genetic hair loss disorder with no effective treatment.
research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats
FGF5 gene mutations cause long hair in domestic cats.
research Mouse Models for the Study of Human Hair Loss
Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
research Insertional Mutation of the Hairless Locus on Mouse Chromosome 14
A gene mutation in mice causes permanent hair loss and skin issues.
research Biology of the Hair Follicle: The Basics
The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
research Hairless Down-Regulates Expression of Msx2 and Its Related Target Genes in Hair Follicles
Hairless protein reduces Msx2 gene activity, affecting hair follicle development.