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Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

Melatonin affects certain genes and pathways involved in cashmere goat hair growth.

Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.

Vitexin Compound 1 may help reduce skin aging caused by UVA light.

New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.

Intermediate filaments are crucial for cell differentiation and stem cell function.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires various treatments to prevent this.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires treatment to prevent malignancy.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

Gray hair can potentially be reversed, leading to new treatments.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.