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The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Fat from the body can help improve hair growth and scars when used in skin treatments.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

SHBG may be a useful early indicator and treatment target for PCOS.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.