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This study observed that quiescent label-retaining cells in the intestine, identified by Paneth cell markers, can switch to a proliferative state and activate Bmi1 expression during tissue injury, contributing to tissue regeneration.

This study found that MAP-2 is intensely expressed in the companion layer of the hair follicle, suggesting its potential importance to follicle integrity and possible involvement in some types of alopecia.

This study observed that inducible deletion of the Ugcg gene in mouse epidermis led to a significant reduction in GlcCers and epidermal POS-Cers, causing impaired skin barrier function and delayed wound healing.

In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.

This study indicates that MPZL3 negatively regulates sebaceous gland size in mice by controlling sebocyte proliferation, with implications for disorders like acne and psoriasis.

This study found that mice lacking CD61 had significantly shorter lower incisors compared to wild-type mice, suggesting CD61 is crucial for proper tooth growth and pre-ameloblast proliferation.

This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.

This study found that cucurbitacin I from bitter melon most effectively inhibited the growth of lung cancer cells and promoted hair cell growth in cell cultures.

This study suggests that targeting olfactory receptors in the lung epithelium might help treat odorant-induced asthma in cases without type 2 inflammation, as these receptors could play a role in airway sensitivity to smells.

This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.

In this study, full-size KRT81 was expressed in both normal breast epithelial and breast cancer cells, and contributed to the migration and invasion abilities of breast cancer cells.

This study found that nexin 1 mRNA, a potent protease inhibitor, is prevalent in rat follicular papilla cells and may play a role in regulating hair follicular growth.

In this case report, researchers described a rare instance of granuloma annulare in a six-year-old child mimicking alopecia mucinosa, highlighting the importance of clinicopathologic correlation in diagnosing dermatological conditions. Treatment with topical mometasone furoate led to a satisfactory improvement and complete resolution within seven months.

This study found that asynchronous differentiation in human anagen hair follicles involves specific localization of c-Myc and interrelated genes Max and Bin1 along the inner root sheath.

In this study, maslinic acid applied topically was observed to stimulate hair growth in mice comparably to minoxidil, primarily activating pathways like Wnt/β-catenin, and suggesting a link between hair growth and cilia activity.

This research observed that Moracin M, a compound from the Moraceae family, significantly promotes hair growth and angiogenesis via the Wnt signaling pathway in human dermal papilla cells, offering a promising alternative to current hair growth treatments like minoxidil.

Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.

This study found that the subtilisin protease Sub3 from Microsporum canis is essential for adherence to the feline epidermis but is not necessary for invading epidermal structures.

This study found that Polycomb Repressive Complex 1 is crucial for maintaining stem cell identity across different lineages, but its loss results in varied transcriptional outcomes depending on the tissue context.

In this study, deleting the gene Mettl3 in mouse epidermal progenitors resulted in impaired epithelial development and self-renewal, highlighting m⁶A's crucial role in regulating chromatin modifiers and maintaining normal epithelial tissue function.

This study found that mice lacking alkaline ceramidase 1 with elevated skin ceramide levels showed disrupted skin homeostasis, including altered hair follicle structures, increased water loss, and a hypermetabolism phenotype.

In this study, researchers developed two novel mouse models to investigate how CD271 deletion in keratinocytes affects skin homeostasis, finding that it leads to changes resembling dysplastic skin conditions with immune cell recruitment and inflammatory cytokine release.

The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.

This study highlights the role of Orai1 in ameloblast differentiation and maturation, showing that its down-regulation affects cell proliferation and enamel formation during tooth development.

This study reported that Moracin M, a compound from the Moraceae family, significantly promoted hair growth and vascular regeneration by enhancing cell proliferation and Wnt signaling activation in laboratory settings, suggesting it may offer a promising alternative to existing hair growth treatments like minoxidil.

This study found that in mouse skin, the activation of stem/progenitor cells is synchronized across different niches during growth, with the glutamate transporter SLC1A3 playing a crucial role in this process.

This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.

In this study, overexpression of ornithine decarboxylase accelerated basal cell carcinoma in Ptch1+/– mice under UVB exposure, while its inhibition reduced tumor induction, suggesting potential chemoprevention strategies in humans.