Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, transgenic mice with a truncated latent transforming growth factor-beta-binding protein showed reduced keratinocyte proliferation and alterations in the hair cycle due to mis-localization of transforming growth factor-beta.

This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.

This study suggests that the downregulation of BBS7 in occlusal hypofunctional periodontal ligament impairs Shh signaling, which is essential for maintaining periodontal ligament homeostasis.

This study found that lncRNA RP11-818024.3 transfection promoted hair growth in AGA mice and increased cellular proliferation in vitro, potentially involving the FGF2 and PI3K-Akt pathways.

This study observed that PCR-based genotyping for cre-loxP mice can lead to errors due to cre-mediated recombination in non-target tissues like tails, affecting the detection of lox alleles.

This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.

In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.

Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.

In this study, researchers found that the congenital absence of the palmaris longus muscle was relatively uncommon and showed no significant differences according to sex, side, or digit ratio (2D:4D) among individuals assessed using MRI and radiographs.

This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.

This study found that mice lacking the type 3 IP(3) receptor in their hair follicles experienced repetitive hair loss and regrowth, indicating disrupted hair-cycle regulation potentially linked to specific signaling pathways.

This study suggests that MMP-9 plays a significant role in extracellular matrix remodeling during hair canal formation in mice, as indicated by delayed hair shaft emergence and hair canal development in MMP-9 knockout mice.

In this study, a patient with recalcitrant lichen planopilaris and frontal fibrosing alopecia showed significant improvement after receiving four doses of the interleukin-23 monoclonal antibody tildrakizumab.

This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.

This case report discusses a rare instance of pseudolymphomatous folliculitis in a 19-year-old man, highlighting the challenge in diagnosing PLF due to its low clinical suspicion index and variable initial clinical diagnoses.

This study observed that the development of the pars intermedia in long-tailed macaques is closely associated with changes in skin pigmentation during pre- and postnatal periods through melanocyte-stimulating hormone and ACTH activity.

This abstract discusses the prevalence and forms of lichen planopilaris, a type of scarring hair loss, but reports no new clinical findings.

In this case report, a rare instance of Graham–Little–Piccardi–Lassueur syndrome coexisting with linear lichen planus was identified in a 35-year-old male, highlighting the condition's rarity in males, with dermoscopy aiding diagnosis through distinctive scalp and trunk lesion features.

This study identified a novel LZTR1 mutation associated with hybrid schwannoma and neurofibroma in a patient with schwannomatosis, but not all cases of hybrid tumors are linked to this condition.

This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.

This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.

This study found that supplementing zinc improved certain developmental defects in mice with the lethal-milk mutation, although it did not increase the survival rate among backcross progeny.

GLABRA2 represses root hair formation by inhibiting a specific gene.

This study found that the mammalian Hr protein can interact with the p53 pathway by binding to a specific p53 response element, influencing the regulation of genes involved in cell cycle control.

PLLA injections can cause hair loss and skin issues.

In this study, repeated pregnancies in a murine model of systemic lupus erythematosus altered skin inflammation and cytokine expression but worsened kidney function and survival compared to controls.

This study found that transgenic expression of Endothelin 3 in mice can maintain a dark pigmentation phenotype independently of Mc1r signaling by regulating melanogenic genes.

This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.

This review discusses prolactin production and regulation in human skin and hair follicles, highlighting its potential broader implications but reports no new empirical results.

This report suggests that patients with primary spontaneous pneumothorax should be evaluated for FLCN mutations, as they may indicate Birt-Hogg-Dube syndrome and associated cancer risks.