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Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Radiation significantly slows down wound healing in mice.

One type of progenitor cell can maintain normal skin in mice.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

NIPP1 is important for healthy skin and could help treat skin inflammation.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Human hair follicle dermal cells can help repair damaged hair follicles.

Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.

Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

Meis1 is crucial for skin health and tumor development.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.

Injected cells show potential for hair growth.