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Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.

Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.

CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.

Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.

Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.

Cholecystokinin may help reduce skin inflammation in psoriasis.

SM04755 may be an effective topical treatment for psoriasis.

SIG-1451 could be a promising new treatment for atopic dermatitis.

The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.

Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.

Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.

Minoxidil absorption in skin is slowed by cleansing, depends on how long it stays on the skin, and is not much affected by reapplication.

Understanding the mouse hair cycle is crucial for cancer research.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.

Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Mobile phone radiation may cause DNA damage in human ear hair follicle cells.

Hair follicle stem cells might help treat traumatic brain injury.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.