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Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.

Skin patterns form through molecular signals and genetic factors, affecting healing and dermatology.

Betamethasone oral mini-pulse therapy showed good or fair results in treating lichen planus.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

White petrolatum jelly is as effective as bacitracin for wound healing without increasing infection rates and can save money.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

New effective scar treatments are urgently needed due to the current options' limited success.

Oestrogens are key for bone growth during puberty in both boys and girls.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride effectively blocks enzyme causing male pattern baldness.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.