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The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Lowering testosterone speeds up wound healing in male mice.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.