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In this study, researchers developed a method to control the valence states of Mo in nanozymes, optimizing their activity for ROS-related therapies, particularly acute kidney injury treatment, and enabling real-time monitoring with photoacoustic imaging.

This study found that transdermal delivery of finasteride using biomimetic Platycladi cacumen-derived nanovesicles enhanced hair regrowth in a mouse model of androgenetic alopecia, outperforming minoxidil by improving skin permeation, reducing oxidative stress, and boosting local drug retention.

In this study, researchers found that massively parallel sequencing of mitochondrial DNA (mtDNA) can improve information recovery from forensic samples, with successful full region amplification possible from as few as 2,000 mtDNA copies, albeit with variability in heteroplasmy among hair samples from the same donor.

This study explores novel alopecia treatments targeting lactate dehydrogenase pathways and improving drug delivery through technologies like phototherapy and soluble microneedles, though practical application challenges remain, necessitating further research for clinical use.

This dataset supports a study suggesting that hair follicle neural crest stem cell-derived exosomes carrying miR-214-3p may promote neurite outgrowth and aid peripheral nerve regeneration in vitro and in vivo.

In this study, an innovative microneedle platform loaded with IGF-1 and modified collagen was reported to significantly promote hair regeneration, enhance neovascularization, and reduce inflammation in a mouse model of androgenetic alopecia, outperforming the commonly used minoxidil treatment.

This review reports that nirmatrelvir-ritonavir has significant drug-drug interactions with many common dermatological medications, whereas molnupiravir may be an alternative therapy due to the absence of such interactions observed so far.

This study found that topical application of N,N-dimethylglycine sodium salt increased dermal blood flow and velocity in human subjects, likely through its effects on endothelial cells and NO-dependent vasodilation.

This study found that bovine milk-derived exosomes (MEV-miRNAs) significantly increased hair follicle dermal papilla cell viability and up-regulated key WNT signaling components in human hair follicles, suggesting potential therapeutic benefits for androgenetic alopecia and telogen effluvium through modulation of hair growth pathways.

In this study, a 68-year-old man with muscle-invasive bladder cancer and renal insufficiency achieved a partial radiological response to neoadjuvant therapy with gemcitabine and Disitamab Vedotin, without significant adverse events, highlighting a potential alternative for cisplatin-ineligible patients.

This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This study found that a gain-of-function mutation in the TRPV3 channel leads to altered hair development in DS-Nh mice by affecting the anagen and telogen phases, highlighting TRPV3's role in hair growth regulation.

This study found that in noise-exposed FVB/NJ mice and cell models, ivacaftor reduced oxidative stress and hearing damage by maintaining CFTR function and increasing Nrf2 expression, suggesting its potential for treating noise-induced hearing loss.

This study found that CMV infection in a mouse model of allogeneic transplantation was associated with increased allo-reactive T cell expansion and exacerbated graft-versus-host disease, highlighting the need for effective GvHD prophylaxis and treatment.

This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.

This study found that Polygoni multiflori Radix water extracts accelerated hair regrowth and hair follicle development in mice, showing a safer profile compared to minoxidil.

This study found that vitamin C deficiency in SMP-30/GNL-KO mice affected gene expression related to hair growth and cell growth, resulting in delayed hair growth compared to those with adequate vitamin C.

This study investigated bovine milk-derived exosomes and found they significantly increased dermal papilla cell viability and up-regulated WNT pathway components in human hair follicles, suggesting potential therapeutic value for hair loss disorders like androgenetic alopecia and telogen effluvium.

This review outlines strategies for preventing, identifying, and managing complications related to current MS therapies and reports no new clinical results, emphasizing the growing complexity in MS treatment regimens.

This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.

Minoxidil and platelet-rich plasma can help turn thin hair into thicker hair in male pattern baldness.

In this study, hair follicle stem cells from ND-GFP transgenic mice were observed to be pluripotent, effectively repairing peripheral nerve and spinal cord injuries in mouse models.

In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.

In this study, researchers observed that nestin-expressing cells in mice can differentiate into blood-vessel-like and nerve-like structures within human melanoma tumors, while bevacizumab treatment altered the origin of these structures to trans-differentiated melanoma cells without significantly impacting tumor growth.

This study developed a nanoemulsion of garlic oil and apple cider vinegar loaded with minoxidil to enhance drug permeation through skin, reporting improved ex vivo skin permeation parameters compared to an aqueous dispersion of minoxidil, suggesting potential benefits for treating alopecia areata.