research Metformin And Malignant Neoplasms: A Possible Mechanism Of Antitumor Action And Prospects For Use In Practice
Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
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research Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model
Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.
research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Topical Application of the Synthetic Triterpenoid RTA 408 Protects Mice from Radiation-Induced Dermatitis
RTA 408 cream protects mice from radiation skin damage.
research Detection of Hair MicroRNAs as Novel Potent Biomarkers: Evaluation of Usefulness for Scleroderma Diagnosis
Hair microRNAs could be effective biomarkers for diagnosing scleroderma.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Systematically Optimized Coenzyme Q10-Loaded Novel Proniosomal Formulation for Treatment of Photo-Induced Aging in Mice: Characterization, Biocompatibility Studies, Biochemical Estimations, and Anti-Aging Evaluation
The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Honokiol Protects Skin Cells Against Inflammation, Collagenolysis, Apoptosis, and Senescence Caused by Cigarette Smoke Damage
Honokiol helps protect skin from damage and aging caused by cigarette smoke.
research Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research New Potential Chemotherapy for Ovarian Cancer: Combined Therapy with WP 631 and Epothilone B
The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.
research Polyphenols Rich Hibiscus Rosa Sinensis Linn. Petals Modulate Diabetic Stress Signaling Pathways in Streptozotocin-Induced Experimental Diabetic Rats
Hibiscus petals improved blood sugar and stress responses in diabetic rats.
research The Pathophysiology of the Male Aging Face and Body
Aging in men is influenced by genetics and lifestyle, leading to muscle loss, bone issues, and skin damage.
research Melatonin Supplement Induced Hair Follicle Development in Offspring Rex Rabbits
Melatonin given to pregnant rabbits improved their babies' fur quality.
research Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction
Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
research Inhibition of Prolactin Promotes Secondary Skin Follicle Activation in Cashmere Goats
Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.
research Equine Hoof Stem Progenitor Cells (HPC) CD29+/Nestin+/K15+ – A Novel Dermal/Epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment
Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
research Changes in Murine Hair with Dietary Selenium Excess or Deficiency
Too much or too little selenium in the diet can cause hair loss and graying in mice.
research Single-Cell Transcriptomics Defines Keratinocyte Differentiation in Avian Scutate Scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research Cisd2 Deficiency Impairs Neutrophil Function by Regulating Calcium Homeostasis via Calnexin and SERCA
Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.
research Selection Signatures in Goats Reveal a Novel Deletion Mutant Underlying Cashmere Yield and Diameter
A specific genetic deletion in goats affects cashmere yield and thickness.
research Clinical Observation of Polycystic Ovary Syndrome Treatment with Resveratrol
Resveratrol improved hormone levels, menstrual cycles, hair loss, and ovarian function in PCOS patients.
research Follicle Hormones
Follicle Stimulating Hormone is important for fertility.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research The Abnormal Skin Structure of Newborn Wistar Rats Maternally Treated with Aspartame: Histological and Immunohistochemical Study
Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.
research Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group
Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.