June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a poly-herbal shampoo with neem, hibiscus, fenugreek, rosemary, and amla, finding that it provides good cleansing, conditioning, and hair-nourishing effects, suggesting it may be a safe and economical alternative to synthetic shampoos.
2 citations
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May 2022 in “Advanced therapeutics” This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.
20 citations
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September 1987 in “The Lancet” 9 citations
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March 1991 in “American Journal of Contact Dermatitis” In this study, 67 patients developed contact dermatitis from using minoxidil for hair loss, with patch tests suggesting it is a frequent sensitizer among topical drugs.
2 citations
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January 2018 in “Indian dermatology online journal” This case report describes a 16-year-old girl who developed Plica Polonica, a rare hair matting disorder, after using a homeopathic antidandruff shampoo, highlighting a potential link between shampoo use and the condition.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a polyherbal antidandruff shampoo using medicinal plant extracts and found it exhibited significant antioxidant and antimicrobial properties, including activity against bacteria and fungi linked to scalp infections, suggesting it as a natural alternative to synthetic shampoos.
September 2024 in “Journal of the American Academy of Dermatology” This review discusses the consensus reached by international experts on guidelines for prescribing and monitoring low-dose oral minoxidil for hair loss, and reports no new clinical results.
25 citations
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January 2019 in “Journal of Pharmacy And Bioallied Sciences” This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.
2 citations
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August 2019 in “PubMed” This abstract reports that topical minoxidil is currently the only FDA-approved treatment for pattern hair loss in both men and women.
July 2019 in “Iconic Research And Engineering Journals” This study found that transparent shampoo bars containing high concentrations of aloe vera gel, castor oil, and cinnamon oil exhibited antimicrobial activity, reduced hair loss, and caused no skin irritation.
July 2018 in “Media Informasi” This study found that a 3:2 combination of pandan leaf and mother-in-law's tongue extracts in hair tonic showed similar hair growth activity as 5% minoxidil after three weeks.
June 2015 in “Reactions weekly” December 2012 in “Reactions weekly” Minoxidil helps hair grow and stand up.
32 citations
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January 2008 in “Journal of Microencapsulation” In this study, nanocapsule-based preparations containing hinokitiol promoted hair growth in mice comparably to Minoxidil solution, as indicated by photographic and histological analysis.
In this survey-based study, researchers found that although scalp tonics are positively perceived for scalp health, minoxidil is viewed negatively due to inconvenient use and side effects, suggesting a need for improved hair loss treatments that enhance safety, effectiveness, and user satisfaction.
July 2025 in “JURNAL BIOLOGI TROPIS” In this animal study, the researchers reported that a shampoo containing 2.5% teak leaf extract and 0.30% virgin coconut oil significantly increased hair growth rate and reduced hair loss in mice, suggesting potential benefits for addressing hair loss.
October 2025 in “International Journal of Advanced Research in Science Communication and Technology” This source reviews recent data on topical minoxidil, evaluating its pharmacology, mechanism of action, clinical effectiveness, and side effects in treating hair loss, although its precise mode of action remains unclear.
37 citations
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May 2016 in “JAAD case reports” This abstract describes monilethrix, an autosomal dominant genodermatosis with symptoms like hair fragility and keratosis pilaris, and does not report new experimental results.
32 citations
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March 2013 in “Journal of Pharmaceutical Sciences” This study observed that iontophoresis significantly improved the delivery of minoxidil sulfate to hair follicles compared to passive methods, suggesting potential benefits for alopecia treatment.
This study observed that liposomes encapsulating minoxidil and PEP penetrate the skin at a slower rate but may reach deeper layers compared to a foam formulation.
2 citations
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September 1991 in “Indian Journal of Dermatology Venereology and Leprology” In this case report, a 25-year-old woman with androgenetic alopecia experienced contact dermatitis from a minoxidil preparation, confirmed by patch tests with both lotion and tablet forms.
January 2025 in “Revista Vitae” In this study, researchers found that 2 out of 9 analyzed cosmetic hair growth products contained the banned substance minoxidil, demonstrating the presence of this antihypertensive drug in some cosmetics despite regulations.
February 2023 in “International Journal of Advanced Research in Science, Communication and Technology” In this study, the researchers investigated the effectiveness of shampoo containing herbal extracts, specifically Neem and Tulsi, for managing dandruff and found it may offer benefits compared to synthetic drugs, which often cause side effects.
January 2026 in “Lumbung Farmasi Jurnal Ilmu Kefarmasian” This study found that a topical emulsion containing purified extracts of sidr leaves and roasted candlenut seeds significantly increased hair growth compared to the base and 2% minoxidil, potentially through their antioxidant and anti-inflammatory properties.
December 2025 in “Saudi Pharmaceutical Journal” This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.
August 2023 in “Scientia Pharmaceutica” In this study, researchers evaluated the stability and color changes of compounded minoxidil formulations used for alopecia, finding that while the formulations remained chemically and microbiologically stable for up to 380 days, significant color changes were observed, which likely do not affect the product's effectiveness.
December 2024 in “Jurnal Syntax Admiration” This study found that MOOEW Hair Tonic had a Return of Investment of over 100%, indicating significant potential for profitable and sustainable business opportunities.
2 citations
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January 2023 In a mouse model, this study found that nano-sized molybdenum accelerated hair growth and reduced oxidative stress markers, with enhancements observed when combined with minoxidil. It suggests potential for this combination as a novel topical treatment for hair loss, pending further clinical validation.
March 2023 in “Reactions Weekly”