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This study found that deletion of c-Jun and JunB in mouse bulge hair follicle stem cells was sufficient to trigger psoriasis-like skin disease through thymic stromal lymphopoietin signaling.

This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.

This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.

This study found that the postnatal thymus contains a population of mesenchymal stem cells that may help maintain functional thymic microenvironments.

This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.

This study found that CD26+ fibroblasts are crucial for effective extracellular matrix production and achieving rapid epidermal and dermal homeostasis in human tissue-engineered skin substitutes transplanted onto rodents.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.

This study found that cocaine disrupted the relationship between certain brain androgen levels and sexual behavior in male rats, with dose-dependent effects on testosterone metabolism.

This study reported that recombinant sonic hedgehog proteins can promote hair growth by activating hair-related genes and signaling pathways, suggesting potential as a therapeutic agent in mice.

This study found that while the EtOAc fraction of Centella asiatica had the highest antioxidant activity, it was toxic to human follicle dermal papilla cells, but the EtOH crude extract promoted hair growth by enhancing VEGF expression.

This study found that dermatologists in the southeastern U.S. often offer less frequent treatment for children with alopecia areata compared to adults, with more treatment also recommended for more advanced stages of hair loss.

This study found that human umbilical cord-derived mesenchymal stromal cell-conditioned media was safe and positively affected hair regeneration in 86.6% of participants in a pilot study.

In this open-label study of post-menopausal women with frontal fibrosing alopecia, researchers found that 12 weeks of baricitinib monotherapy significantly reduced disease activity as measured by the Lichen Planopilaris Activity Index, improved patient-reported scalp hair growth, but showed no significant change in eyebrow growth.

In this clinical study, Verilich hair serum significantly reduced hair shedding by 40% or more in 75% of female patients with Telogen Effluvium and Female Pattern Hair Loss after one month of use.

This study details a method for assessing the risk of modifications to pharmaceutical frame formulations by assigning a risk priority number using Failure Modes Effects Analysis, which estimates the severity and probability of changes impacting the formulation.

The document concludes that scalp conditions have various causes and can present in many different ways.

Some alternative treatments may help with hair loss, but more evidence is needed to confirm their effectiveness.

This review discusses the application of low-level light therapy for hair loss treatment, particularly androgenetic alopecia, and reports no new clinical results; the authors suggest consideration of light source characteristics and potential pros and cons.

In this review, researchers explored how lifestyle interventions like exercise, sleep improvement, stress management, nutrition, and mind-body techniques can positively influence the general health and outcomes of patients with chronic inflammatory skin disorders such as hidradenitis suppurativa and psoriasis.

This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.

This article provides issue information and does not include an abstract or any new research findings.

This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.

This study suggests that hair follicle dermal stem/progenitor cells play a key role in both hair regeneration and skin wound healing, with potential implications for preventing hair follicle miniaturization linked to aging or alopecia.

This study found that veterans with obstructive sleep apnea were nearly twice as likely to develop herpes zoster compared to those without the condition.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.

This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.

This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.