research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
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research Effectiveness of Ethinylestradiol/Chlormadinone Acetate in Treating Dermatological Conditions Related to High Androgen Levels
The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.
research Tinea Capitis
Tinea capitis is a fungal infection of the scalp that mainly affects children and can cause symptoms from mild itching to severe inflammation.
research S124 Variants of Myxoid Cysts: Diagnosis and Treatment
Common hair loss can be diagnosed with a physical exam and sometimes a hair test or skin biopsy, and treated with medication or surgery, with ongoing treatment needed to keep results.
research Issues in Transgender Dermatology: A Systematic Review of the Literature
The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.
research Pain Management in Photoepilation
Effective pain relief methods for photoepilation include topical anesthetics, cooling devices, and skin stimulation.
research Cells to Surgery Quiz: April 2020
Certain surgical methods are better than routine incision for hidradenitis suppurativa, topical clindamycin and acitretin are effective treatments, men with HS have a risk of skin cancer, HS patients are more likely to die from heart problems, and specific genetic markers are linked to treatment response.
research Journal Watch
A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
research Spironolactone in Dermatology: Uses in Acne and Beyond
Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
research Understanding Polycystic Ovary Syndrome
PCOS affects many women, causing various symptoms and health risks, and is managed through lifestyle changes, medication, and support groups.
research Highly Efficient and Compatible Shampoo for Use After Hair Transplant
The shampoo is very effective and safe for use after hair transplants.
research Trichotillomania: Bizarre Pattern of Hair Loss in an 11-Year-Old Girl
An 11-year-old girl with compulsive hair pulling was successfully treated with therapy and medication.
research Is the Effect Worth the Risk? The Most Common Complaints During Oral Isotretinoin Anti-Acne Therapy and Controversies Around Its Adverse Effects
Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.
research Ptosis in Childhood: Causes, Clinical Presentations, and Management
Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.
research Clinical Profile of 50 Premenopausal Women with Hirsutism
Most women with hirsutism have mild symptoms and often experience acne, menstrual irregularities, and obesity.
research Safety of Testosterone Use in Women
Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
research Prevalence of Itch and Pain in Patients with Mild to Moderate Chronic Venous Insufficiency at Parkland Memorial Hospital (2005)
Itch is a common symptom in patients with chronic venous insufficiency, often worsening with standing or sitting and occurring mostly in the evening or at night.
research Post-Finasteride Adverse Effects in Male Androgenic Alopecia: A Case Report of Vitiligo
Finasteride may cause vitiligo, sexual issues, and depression; better treatments and predicting side effects needed.
research Hair Removal With Intense Pulsed Light
Intense pulsed light (IPL) is an efficient and safe method for hair removal, reducing hair by about 80%.
research Safety of High-Dose Vitamin A
High-dose vitamin A was safe and well-tolerated in a lung cancer treatment study.
research Chronic Toxicity of 3,4,3′,4′-Tetrachlorobiphenyl in the Marmoset Monkey (Callithrix Jacchus)
High doses of TCB cause severe health issues in marmoset monkeys.
research Use of Beard Hair as a Donor Source to Camouflage Linear Scars of Follicular Unit Hair Transplant
Beard hair can effectively hide hair transplant scars.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Long-Term Satisfaction and Tolerability with Low-Dose Flutamide: A 20-Year Surveillance Study on 120 Hyperandrogenic Women
Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.
research Erosive Pustular Dermatosis of the Scalp: A Pathogenetic Mystery and Therapeutic Challenge
A rare scalp condition called Erosive pustular dermatosis is hard to diagnose and treat.
research Rothmund-Thomson Syndrome Type 2 – A Rare Cause of Chronic Wounds
Rothmund-Thomson syndrome type 2 can cause chronic, poorly healing wounds.
research Cicatricial Alopecia with Particular Trichoscopic and Histopathological Features
The document concludes that a woman has both Frontal Fibrosing Alopecia and Lichen Simplex Chronicus, a previously unreported combination of conditions.
research Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in Screening
The case emphasizes the need for careful screening in children for insulin resistance and related conditions.
research Adapalene–Benzoyl Peroxide, A Unique Fixed-Dose Combination Topical Gel For The Treatment Of Acne Vulgaris: A Transatlantic, Randomized, Double-Blind, Controlled Study In 1670 Patients
The adapalene-benzoyl peroxide gel works better and faster for acne treatment than using either ingredient alone, with manageable side effects.
research Anti-Androgens: Their Use in Dermatology
Cyproterone acetate with ethynyl estradiol significantly improved acne and seborrhea in women, but was less effective for hair loss and excessive hair growth.