June 2020 in “Journal of Investigative Dermatology” This study found that increasing commensal bacterial load on the skin enhances wound-induced hair follicle neogenesis in mice, mediated through IL1R-MyD88 signaling pathways.
22 citations
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March 2018 in “American Journal of Clinical Dermatology” New acne treatments show promise as alternatives to traditional therapies.
16 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.
December 2025 in “Progress in Biomedical Engineering” This article reviews emerging mechanobiological strategies like electrical stimulation and microneedling combined with nanotechnology as non-invasive methods for hair loss treatment, suggesting these approaches could provide futuristic alternatives to current therapies such as minoxidil, finasteride, and hair transplants.
In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.
June 2020 in “Medicinskij alfavit” In this clinical study of 98 patients with focal alopecia, combined laser therapy, which included laser plasma therapy and percutaneous laser irradiation of blood, was reported to alleviate inflammation, promote hair growth, and restore trace elements in affected areas.
November 2025 in “Medical alphabet” This study highlights that physiotherapeutic methods like low-intensity laser therapy, radiofrequency, and electrical stimulation show promising effectiveness in stimulating hair growth and treating telogen effluvium by enhancing cell activity, ATP synthesis, and transdermal drug delivery.
This case report highlights the successful use of platelet-rich plasma infiltration to treat vasopressin-induced bilateral foot digit gangrene in a 20-year-old female, suggesting its potential in stimulating angiogenesis and wound healing, though further research is necessary to assess its general efficacy.
1 citations
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January 2026 This study outlined modern approaches for using cosmeceuticals in trichology, emphasizing evidence-based medicine, personalized care, and patient safety. It proposed the H.A.I.R. model as a universal algorithm for trichological programs and suggested new educational and practical tools for specialists in trichology and aesthetic medicine.
January 2026 in “International Journal of Applied Pharmaceutics” This review discusses the integration of nanoparticles with microneedles to improve drug delivery through enhanced stability, bioavailability, and controlled release, noting ongoing challenges with stability, scalability, and safety.
6 citations
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February 2022 in “Journal of immunology research” This study observed that exosomes from adipose-derived stem cells promoted hair growth by enhancing dermal papilla cell proliferation and activating signaling pathways, suggesting potential for treating immune-mediated alopecia.
9 citations
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May 2021 in “Archives of Dermatological Research” This study concluded that while home-based intense pulsed light, laser diodes, radiofrequency, and light-emitting diode devices are recommended for certain skin conditions, ultraviolet B phototherapy for psoriasis showed mixed evidence compared to clinic treatments.
1 citations
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January 2025 in “BIO Integration” This review highlights that the combination of ultrasound and microneedles can enhance transdermal drug delivery by using physical and energy-driven mechanisms to improve drug penetration into deeper skin layers, with implications for precision medicine and chronic disease treatments.
January 2026 in “MEDS Clinical Medicine” This review discusses the combined use of plum-blossom and Daoma needle therapy for androgenic alopecia, emphasizing its potential benefits and the need for further clinical research, but reports no new results.
March 2023 in “Anais Brasileiros De Dermatologia” This article reviews treatment options for female-pattern hair loss, noting the limited evidence for most therapies and emphasizing that topical minoxidil remains the only well-supported option despite a significant non-response rate.
November 2025 in “Indian Journal of Dermatology” This research guide explores the diverse types, functions, benefits, and considerations of home-based dermatology devices, emphasizing their convenience, cost-effectiveness, and privacy benefits, while also warning of potential risks like improper use and limited effectiveness compared to professional treatments.
1 citations
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August 2024 in “European Journal of Medicinal Chemistry Reports” This systematic review examines the landscape of cosmetic microneedling using SWOT analysis, identifying strengths like precise delivery and self-administration, while noting challenges such as potential skin damage and regulatory issues, with opportunities in AI-enhanced targeted treatments noted by these researchers.
1 citations
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January 2022 in “Stem cell biology and regenerative medicine” This review describes various in vitro and ex vivo hair follicle models used to study hair growth and regeneration and explores their potential for developing hair loss treatments, but it does not report new results.
March 2025 in “Journal of Cutaneous and Aesthetic Surgery” This study highlights promising advancements in non-invasive techniques for treating hair-related conditions, emphasizing the importance of customizing treatments based on individual needs.
48 citations
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September 2017 in “Frontiers in Bioscience” This review explores the role of nanotechnology in wound healing, highlighting its potential through antimicrobial properties, selective inflammatory action, angiogenesis promotion, and its use in drug and gene delivery.
September 2023 in “Frontiers in medicine” This review suggests that the mTOR signaling pathway may play a significant role in hair follicle health by influencing the effects of Vitamin D receptor deficiency, potentially contributing to hair follicle damage and related hair loss conditions.
19 citations
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September 2015 in “Therapeutic Delivery” This review discusses the application of active transdermal technologies in cosmetic devices for skin restoration and enhancement, reporting no new clinical results.
14 citations
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May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
2 citations
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March 2025 in “Nanoenergy Advances” This review examines recent advances in bioelectronic nanogenerators for anti-cancer therapy, highlighting various transducing strategies such as photodynamic therapy and electrical stimulation, while also discussing the potential mechanisms for tissue repair and the challenges that lie ahead.
4 citations
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May 2022 in “International journal of molecular sciences” This study found that heat-killed Enterococcus faecalis EF-2001 promoted hair regrowth in mice, likely by increasing the expression of growth factors and marker genes.
8 citations
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October 2022 in “Regenerative Therapy” This review discusses regenerative medicine approaches for treating alopecia, including mesenchymal stem cell therapies and platelet-rich plasma, but reports no new clinical results, emphasizing the need for further study.
January 2025 in “Medicina” This study reviews emerging techniques in acute burn wound therapy, noting innovations such as advanced imaging for better wound assessment and new closure strategies aimed at improving healing, graft survival, and scarring outcomes, while emphasizing the need for further research to validate these methods.
1 citations
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March 2024 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study on albino mice, Helianthus annuus and Martynia annua seed oil extracts in petroleum ether significantly promoted hair growth in a dosage-dependent manner, with 30 mg/ml showing notable results compared to 2% minoxidil.
1 citations
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December 2022 in “Animals” This study found that miR-27a may influence sheep hair follicle stem cell proliferation and apoptosis by targeting PIK3R3, affecting the AKT/MTOR pathway.
October 2024 in “Cosmetics” In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.