74 citations
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June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that hair follicles are a significant and efficient pathway for the absorption of topical minoxidil foam in humans, with faster blood detection when follicles are open.
223 citations
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October 2020 in “Microsystems & Nanoengineering” This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.
29 citations
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September 2014 in “American Journal of Dermatopathology” This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.
July 2026 in “Frontiers in Bioengineering and Biotechnology” This mini-review reports that advances in microbioreactor technology, particularly with microfluidics, significantly enhance eukaryotic cell-based biomedicine by improving productivity, scalability, and reproducibility in applications like CAR T-cell manufacturing and organoid growth, though challenges in scalability and material selection remain.
January 2013 in “프로그램북(구 초록집)” This study found that using a 0.5mm roller for microneedle therapy increased hair growth in mice and significantly affected the expression of hair growth-related molecules like VEGF.
8 citations
,
January 2011 in “Experimental and Therapeutic Medicine” This review summarizes the characteristics of the peri-malignant melanoma stroma, indicating its potential role in early dermal metastatic migration and increased metastasis risk.
14 citations
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April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
May 2026 in “Skin Appendage Disorders” This study identified distinct trichoscopic and histopathological features of telogen effluvium following COVID-19 infection, with trichoscopic vascular patterns correlating with the severity of the initial infection.
19 citations
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May 2020 in “Cells” This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.
7 citations
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March 2003 in “PubMed” This study reported that in men with androgenic alopecia, a distinct subclinical hyperpigmentation pattern was observed in the scalp, associated with baldness severity and possibly linked to local melanin production by pilosebaceous units.
October 2025 in “Bioactive Materials” This review highlights the potential of microneedle technology in traditional Chinese medicine as a promising transdermal delivery system for skin diseases, showcasing improved efficacy and reduced side effects of TCM ingredients while discussing the challenges of its clinical application.
182 citations
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December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” This study demonstrated that hair follicles significantly expedite the absorption of caffeine through the skin compared to interfollicular pathways.
2 citations
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August 2019 in “Electronics and Communications in Japan” This study reports a highly sensitive MEMS silicon-hair device that mimics hair follicle functions by detecting minimal forces and moments, including electrostatic attraction and surface tension of liquids.
January 2026 in “British Journal of Dermatology” This study found that neither caffeine nor N,N-dimethylglycine treatments were toxic to balding or nonbalding dermal papilla cells and could stimulate calcium influx, indicating treatment responsiveness.
March 1990 in “Journal of Dermatological Science” 1 citations
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February 2023 in “American Journal of Dermatopathology” Microscarring is found in both alopecia areata and pattern hair loss, suggesting a shared cause.
2 citations
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February 2023 in “Anais Brasileiros de Dermatologia” April 2026 in “Journal of Investigative Dermatology” This research observed that diabetes impairs wound healing in mice by disrupting key mechanotransduction pathways in fibroblasts, which are crucial for the healing process. The study also suggests transcriptomic changes could inform future diabetic wound repair therapies.
17 citations
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January 2024 in “Burns & Trauma” The researchers reported that exosomes from hypoxic M2 macrophages, enriched with miR-26b-5p, promoted proliferation, migration, and invasion in human keloid fibroblasts through the PTEN-PI3K/AKT pathway, highlighting miR-26b-5p's role in keloid development.
11 citations
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July 2023 in “Applied Nanoscience” This study found that S1PR1 signaling in mouse aortic endothelial cells varied by location and subtype, influencing inflammatory and lymphangiogenic gene expression through distinct molecular pathways.
27 citations
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March 2006 in “Dermatologic surgery” This review discusses the widespread acceptance of micropigmentation for cosmetic purposes and its various medical applications, but reports no new clinical findings.
29 citations
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October 2010 in “Acta Biomaterialia” March 2021 in “Postepy Dermatologii I Alergologii” In this study, topical 5% minoxidil significantly increased total hair count in women with female pattern hair loss after 6 months, and scalp vascularization did not affect treatment efficacy.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reported that distinct stem/progenitor populations in the ocular surface epithelium have different cell division frequencies and respond differently to injury, with specific spatial compartmentalization and migration behaviors.
19 citations
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September 1999 in “Talanta” New method measures minoxidil concentration faster, more accurately, and automatically.
This study found that targeting S1PR1 signaling in mouse aortic endothelial cells helps suppress inflammation-related gene expression while revealing diverse and spatially distinct endothelial cell subtypes.
January 2002 in “中国人民解放军军医大学学报:英文版” This study found that real-time 2-D Doppler echo of intracardiac blood flow helps evaluate myocardial infarction severity, with persistent late systolic inflow indicating worse left ventricular function.
September 2017 in “Journal of Investigative Dermatology” QMSI effectively maps and quantifies drug distribution in skin tissues.