13 citations
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June 2024 in “BMC Genomics” This study found distinct expression patterns of various transcription types during hair follicle morphogenesis, providing a foundation for understanding hair development mechanisms and aiding selective breeding for desirable wool traits in a specific breed.
10 citations
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November 2024 in “Animals” This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.
7 citations
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January 2017 in “Stem Cells International” This review categorizes current research on neural organogenesis and highlights potential future applications for treating central nervous system diseases, but reports no new clinical results.
6 citations
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January 2015 in “Journal of regenerative medicine & tissue engineering” This review discusses the role of stem cells and tissue engineering in regeneration and transplantation, emphasizing the need for advanced technologies to improve treatments for injuries and disabilities, but reports no new results.
5 citations
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November 2022 in “Diversity” This review highlights the potential of indigenous southern African foods rich in phytochemicals and soluble dietary fibers to combat cardiovascular disease in economically disadvantaged urban populations in South Africa by improving dietary diversity and affordability.
5 citations
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September 2012 in “BMJ case reports” This case study reports that a woman with non-classical adrenal hyperplasia who self-treated with Ashwagandha for six months experienced biochemical improvements and reduced scalp hair loss.
3 citations
,
May 2025 in “Journal of Ovarian Research” This review discusses the recent progress in understanding the role of m6A modifications in the development of polycystic ovary syndrome and reports no new clinical findings.
3 citations
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May 2023 in “Biomedicines” This article reviews the immunometabolic mechanisms linking polycystic ovary syndrome to infertility and stresses the need for interdisciplinary approaches to treat PCOS-related fertility issues; it reports no new clinical results.
2 citations
,
October 2023 in “Biology” This review highlights cobalt's essential role in vitamin B12 metabolism and its biomedical applications but also warns of health risks from high levels and environmental contamination, discussing remediation methods like phytoremediation.
1 citations
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September 2023 in “Stem cell research & therapy” This review discusses how mesenchymal stromal cell-based therapy holds promise for treating age-related diseases, given its potential to target aging's pathological features, although significant challenges remain for its clinical application.
1 citations
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January 2019 in “Archives of Clinical and Medical Case Reports” In this study, researchers identified two mechanisms of lipid loss from hair when exposed to surfactants, with the mechanism depending on the lipid's hydrophobicity.
April 2026 in “The Open Biotechnology Journal” This review reports that resveratrol could benefit the management of chronic illnesses such as diabetes and cardiovascular disease, but challenges with bioavailability and regulatory issues persist.
January 2026 in “Metabolites” This study analyzed gene expression profiles from multiple tissues to explore the molecular connections between obesity and immune-related processes, identifying potential links and pathways that may require further experimental validation to understand their roles in obesity fully.
December 2025 in “Journal of Cosmetic Dermatology” This study found that finasteride use is not significantly associated with an increased risk of depression or suicide, based on Mendelian randomization analysis and COX regression analysis in a large UK Biobank cohort.
October 2025 in “Gene Expression” This review explores the potential of exosomes, which contain substances that may stimulate hair follicle activity, as a new therapeutic strategy for alopecia, and discusses their possible benefits and risks based on current knowledge of microRNAs and intracellular signaling in hair follicle morphogenesis.
September 2025 in “Pharmaceutics” This review examines recent advances in androgenetic alopecia treatment, highlighting how multifunctional plant extracts combined with nanotechnology could improve topical therapy efficacy by enhancing local drug bioavailability and targeting, addressing limitations of existing treatments.
August 2025 in “International Journal of Molecular Sciences” This study found that compounds isolated from Osmanthus fragrans var. aurantiacus demonstrated antioxidative and anti-inflammatory activities, potentially offering therapeutic benefits for inflammatory bowel diseases by inhibiting COX-2 and iNOS enzymes and blocking ERK 1/2 MAPK signaling.
June 2025 in “Academic Medical Journal” This study suggests elevated homocysteine levels may serve as a biomarker for disease severity and vascular risk in cutaneous lupus erythematosus, indicating potential therapeutic benefits from B-vitamin supplementation and lifestyle changes.
April 2025 in “Materials Today Bio” In this study, researchers demonstrated that self-assembled gold nanoclusters with aptamers effectively deliver anti-NFκB aptamer drugs to inhibit hair follicle regeneration while being non-toxic to normal cells, offering a targeted treatment for hypertrichosis.
February 2024 in “Biomedicines” This study found that NKB placental mRNA expression was higher in women with PCOS, particularly in pregnancies with female offspring, suggesting its involvement in PCOS-related placental dysfunction.
December 2022 in “Journal of neurodevelopmental disorders” This study observed that repeated hair follicle sampling is feasible and reliable for measuring FMR1 mRNA and FMRP in individuals with Fragile X syndrome, supporting its use in longitudinal studies.
January 2022 in “IntechOpen eBooks” This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.
November 2020 in “IntechOpen eBooks” This review discusses the role of mineral nutrients in human health, emphasizing the importance of dietary sources and education to prevent mineral deficiencies, and reports no new clinical results.
110 citations
,
February 2024 in “Journal of Chemical Information and Modeling” This study describes the PandaOmics platform, which uses AI and bioinformatics to identify new therapeutic targets and biomarkers for various diseases, demonstrating validation in laboratory and animal studies.
31 citations
,
August 2021 in “Stem Cell Research & Therapy” This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.
10 citations
,
December 2023 in “International Journal of Nanomedicine” This study reviewed the challenges of delivering nucleic acids for gene therapy, highlighting the limitations of non-viral vehicles and exploring bioinspired strategies using cell membrane camouflage for improved delivery efficacy.
7 citations
,
August 2019 in “Aesthetic Plastic Surgery” Both surgical and non-surgical hair loss treatments lack a standard treatment plan and sufficient patient satisfaction data.
3 citations
,
September 2014 in “SpringerPlus” This study suggests that hair loss was a metabolic adaptation allowing hominids to evolve larger brains by alleviating dietary restrictions on essential amino acids for hair and brain development.
1 citations
,
July 2024 in “International Journal of Molecular Sciences” In this review, researchers introduced clinically tunable siRNA delivery systems for hair loss treatment, discussing design principles and analyzing relevant clinical trials to propose a framework for optimizing siRNA delivery in a clinical context.
1 citations
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January 2020 in “Bioscience Reports” This study found that prolonged use of finasteride in women led to altered levels of sex steroids, DNA damage, and increased menstrual bleeding, suggesting adverse health effects without clear benefits for androgenetic alopecia treatment.