Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the roles of sebaceous gland activity, Malassezia yeast, and individual susceptibility in scalp flaking disorders, including dandruff and seborrheic dermatitis, but reports no new experiment results.

This review explores links between metabolic syndrome and skin diseases, reporting shared mechanisms like inflammation and hormonal imbalances that may influence conditions such as acne, rosacea, psoriasis, and alopecia, and emphasizes the importance of managing cardiovascular risks in affected patients.

This study found a consistent association between atopic dermatitis and obesity, while links with other metabolic syndrome components like dyslipidemia and hypertension were inconsistent, indicating the need for targeted metabolic screening, particularly in moderate-to-severe cases.

This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.

This review discusses the link between metabolic syndrome and various inflammatory skin diseases and reports no new clinical results, emphasizing the importance of recognizing skin manifestations as early indicators of systemic metabolic disorders.

This meta-analysis found a strong association between metabolic syndrome and certain skin diseases, including psoriasis, hidradenitis suppurativa, androgenetic alopecia, and lichen planus, suggesting increased risk compared to the general population.

This study discusses the multifactorial causes of metabolic syndrome and its association with various skin conditions, indicating an increased risk of diabetes and cardiovascular issues, emphasizing the need for early lifestyle interventions and medical management.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

In this study, the researchers found that deleting ceramide synthase 4 in the skin's epidermis alters stem cell differentiation, disrupting hair follicle structure and barrier function, potentially leading to immune responses similar to atopic dermatitis.

This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.

This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.

This narrative review explores the strong association between various chronic inflammatory skin diseases and metabolic syndrome, emphasizing shared inflammatory pathways and chemokine involvement, though the precise molecular connections remain partially understood.

This review discusses the skin manifestations associated with metabolic syndrome and related conditions in young populations, noting associations with obesity, insulin resistance, and neonatal obesity, but reports no new clinical results.

This study describes five patients whose cystic fibrosis was initially indicated by a rash associated with protein-energy malnutrition, highlighting the importance of early symptom recognition for timely diagnosis and treatment.

This study identified secondary copper deficiency in Thanjavur black goats as a possible cause of alopecia and other skin issues, despite adequate dietary copper, indicating impaired copper absorption or metabolism.

This study found that male germ-free rats fed semisynthetic diets do not grow as rapidly as their conventional counterparts and require dietary biotin for normal metabolism and folic acid biosynthesis.

This study found that a nutritional intervention in dogs led to changes in skin microbiome and immune-related gene expression, with reduced levels of certain fungal pathogens and a potential alleviation of atopic dermatitis symptoms.

This study found that 69.89% of patients with metabolic syndrome attending primary healthcare in Gurupi, Brazil, exhibited dermatological manifestations, with morbid obesity strongly linked to these skin changes.

This study reported successful treatment of biotin deficiency in three patients receiving total parenteral nutrition, suggesting current biotin supplementation recommendations may be inadequate to maintain normal biotin status.

This study documented a case of an 11-month-old with PKU who developed acrodermatitis enteropathica-like symptoms due to severe phenylalanine deficiency, requiring dietary adjustment to restore phenylalanine levels.

This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.

This study found that acne keloidalis nuchae was associated with pseudofolliculitis barbae, chronic scalp folliculitis, and aspects of the metabolic syndrome, particularly hypertension, in the examined population.

This study reviewed current scientific evidence on how scalp microbiome alterations may affect hair growth, citing connections to inflammatory and immune processes and suggesting potential for therapeutic targeting, though further studies are needed to confirm clinical applications.

This review discusses the associations between dermatological disorders and increased cardiovascular risk, emphasizing that skin conditions with chronic inflammation may elevate the likelihood of cardiovascular diseases.

This case study reports a two and a half-month-old with biotinidase deficiency who showed rapid seizure improvement with biotin treatment after presenting with convulsions and neurological symptoms.

This review summarizes recent findings on the role of lactylation, a novel post-translational modification, in skin diseases, suggesting its potential as a therapeutic target by linking metabolism, epigenetic regulation, and inflammatory processes.

This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.

This study found that while biotin treatment improves clinical and biochemical symptoms in patients with biotinidase deficiency, some experience lasting neurological damage, and it is uncertain if early treatment can prevent this.

Ceramide Synthase 4 is crucial for healthy skin barrier function.

In this case report, a 6-year-old male with biotinidase deficiency experienced marked improvement in dermatological symptoms, including alopecia and periorificial lesions, following biotin treatment.